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苯唑西林钠联合糖皮质激素治疗葡萄球菌性烫伤样皮肤综合征疗效观察

Effect Observation of Treating Staphylococcal Scalded Skin Syndrome with Oxacillin sodium Plus Glucocorticoid
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摘要 目的:探讨苯唑西林钠联合糖皮质激素治疗葡萄球菌性烫伤样皮肤综合征的效果。方法:选择葡萄球菌性烫伤样皮肤综合征患者52例,随机分成两组,治疗组28例,用苯唑西林钠(100mg/kg·d)联合地塞米松(0.15mg/kg·d)分别静脉滴注,连用3天后减量停药;对照组24例,单纯用苯唑西林钠(100mg/kg·d)静脉滴注,然后观察两组疗效。结果:治疗组触痛消失,皮肤松解症状缓解,皮疹消退时间和痊愈时间均较对照组缩短,有显著性差异(P<0.05)。结论:苯唑西林钠联合地塞米松治疗葡萄球菌性烫伤样皮肤综合征疗效明确,可缩短病程,值得推广。 Objective: To observe the effect of treating staphylococcal scalded skin syndrome with Oxaeillin sodium plus Glucocorticoid. Method: Selected 52 patients with staphylococcal scalded skin syndrome were divided into treatment group ( n = 28) and control group ( n = 24 ) . In treatment group, the patients were given Oxacillin sodium ( 100mg/kg . d) and dexamethasone (0. 15mg/kg . d) injection by intravenous drip successively for 3d, while in control group, only Oxacillin sodium ( 100mg/kg . d) was dripped via intravenous. The effect in the two groups were observed and compared. Results: The feeling of haphalgesia of skin disappeared and the skin loosening symptoms improved were observed, Rash subsided and recovery time in the treatment group was shorter than that in control group. There were significant differences (P 〈 0. 05 ) between two groups. Conclusion: It is worthy of popularization to treat staphylococcal scalded skin syndrome with Oxacillin sodium plus Glucocorticoid because of its marked efficacy and shorter course.
出处 《中国烧伤创疡杂志》 2010年第3期207-208,共2页 The Chinese Journal of Burns Wounds & Surface Ulcers
关键词 苯唑西林钠 糖皮质激素 葡萄球菌性烫伤样皮肤综合征 Oxacillin sodium Glucocorticoid Staphylococcal scalded skin syndrome
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