摘要
目的：了解慢性心力衰竭（CHF）患者贫血的发生率及其对住院期间死亡的影响。方法：收集2003-01-2008-06在我院住院的CHF患者的临床资料进行回顾性分析,根据患者血红蛋白（Hb）水平分为Hb正常组、轻度贫血组以及中重度贫血组3组。结果：贫血在CHF患者的发生率为32.5%;住院期间死亡患者的Hb、RBC均明显低于好转的患者（P〈0.01）,贫血患者在住院期间的死亡率明显高于无贫血的患者（P〈0.01）,以二分类Logistic回归住院期间死亡的危险因素进行分析得出：贫血的偏回归系数为1.296（P=0.039）,优势比（OR）为3.655（95%CI：1.069-12.499）;对于心功能NYHAⅢ-Ⅳ级的CHF患者,Hb的偏回归系数为-0.073（P=0.041）,OR为0.93（95%CI：0.864-0.995）。结论：CHF患者贫血的发生率较高,贫血是CHF患者住院期间死亡的独立危险因素,Hb降低增加心功能Ⅲ-Ⅳ级的CHF患者住院期间的死亡。
Objective：To investigate the morbidity of anemia in patients with chronic heart failure （CHF） and its prognostic role in predicting death during hospitalization.Methods：The clinical data of patients with CHF were collected, and analyzed according to the hemoglobin （Hb） levels in serum.Results：The morbidity of anemia was 32.5% in patients with CHF, and the rate of death in CHF patients with anemia was higher than those without anemia （P〈0.01）. Meanwhile, the levels of Hb and red blood cell count （RBC） were significantly decreased in died patients compared to those in survived patients during hospitalization （P〈0.01）. The results of analysis by binary logistic regression showed that the coefficient of partial regression was 1.296 （P=0.039） and the odds ratio （OR） was 3.655 （95% CI：1.069-12.499） for anemia. But for Hb in patients with CHF of NYHA Ⅲ-Ⅳ, the partial regression coefficient was -0.073 （P=0.041） and the OR was 0.93 （95% CI： 0.864-0.995）, respectively.Conclusion：The morbidity of anemia was high in patients with CHF, and anemia was a independent risk factor for death during hospitalization in patients with CHF.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2010年第4期247-250,共4页
Journal of Clinical Cardiology
关键词
慢性心力衰竭
贫血
危险因素
预后
chronic heart failure
anemia
risk factor
prognosis
