摘要
目的:探讨低分子肝素联合小剂量阿司匹林治疗不稳定性心绞痛(UAP)的疗效。方法:采用随机分组,将52例不稳定性心绞痛患者分为两组。治疗组:低分子肝素(速避凝)0.4ml。皮下注射1次/天,连用7天,加服阿司匹林75mg/d。对照组:口服阿司匹林75mg/d。观察治疗前后不稳定性心绞痛发作频率及发作持续时间的变化。结果:低分子肝素联合小剂量阿司匹林治疗不稳定性心绞痛发作频率减少,发作持续时间缩短,与对照纽差异均有显著性(P〈0.01)。结论:低分子肝素联合小剂量阿司匹林治疗不稳定性心绞痛疗效显著。
Objective:Texamine the efficacy of low-molecular in combination withaspirin in treatment of postinfarction unsteady angina pectoris.Methods: fifty-tow postinfarction unsteady angina pectoris patients were randomly divided in tow group. Cure group: low-molecular heparin 0.4ml/d injected subcutaneously for seven days plus aspirin 75mg/d.Control group:aspirin75mg/dwas administered and the paroxysmal frequency,paroxysmal panes and side effects were observed before and after the drug therapy. Result:The frequency and duration of angina pectoris attacks in the cure group decreased significantly compared with those in the control group (p 〈 0.01) And few side effects were found. Conclusions:Low-molecular heparin in combination with aspirin are more effective than aspirin alone in the treatment of postinfarction unsteady angina pectoris.