摘要
目的:探讨肝素在预防过敏性紫癜性肾炎中的疗效及安全性。方法:采用随机对照的方法,将98例过敏性紫癜患儿分为肝素治疗组(49例)和对照组(49例),肝素组给予肝素钠100～150 U加入5%葡萄糖100～200 mL中静脉点滴,每日1次,连用5～7天,以后每两周查尿常规1次,至少观察3个月或以上。结果:肝素治疗组发生肾炎3例(6.1%),对照组发生肾炎11例(22.4%),肝素治疗组肾炎发生率低于对照组(0.01<P≤0.05)。结论:肝素对预防紫癜性肾炎的发生有效,且不良反应少。
Objective：To investigate the heparin in the prevention of allergic purpura nephritis in the efficacy and safety.Methods：A randomized-controlled method,98 cases of allergic purpura patients were divided into heparin in the treatment group（49 cases） and control group（49 cases）,heparin group received heparin,100-150 u in 5%glucose 100～200 mL in the intravenous drip,day 1,used in conjunction 5-7 days,after a routine urine check every two weeks times,at least for 3 months or more.Results：The results of heparin treatment group occurred nephritis in 3 cases （6.1%）,glomerulonephritis in 11 cases in control group（22.4%）,glomerulonephritis incidence of heparin in the treatment group than the control group（0.01P≤0.05）.Conclusion：heparin in preventing the occurrence of Henoch -Schonlein purpura nephritis and effective,and less adverse reactions.
出处
《华西医学》
CAS
2009年第11期2934-2935,共2页
West China Medical Journal
