摘要
目的：通过流体模型,检验3.0T磁共振相位对比法（3.0T PC-MRI）速度编码值（Venc）、编码方向的选择及其对流体动力学定量测量的准确性和稳定性。方法：固定流速和Venc,检验不同编码方向下的流体信息;固定Venc和编码方向,检验PC-MRI对不同注射流率（0-5 ml/s）所测流速值与标准流速的差别,采用配对样本t检验以检验二者差异性。结果：只有选择SLICE或SI编码方向才能正确反映质子流动的方向;在Venc适当大于实际流速时,不同注射流率PC-MRI流速测量值与流速真实值之间差异无统计学意义（t=-0.861,P〉0.05）,二者呈显著正相关关系（r=0.999,P〈0.001）。结论：选择正确的Venc和编码方向是准确测量流体动力学的前提,3.0T PC-MRI能客观、准确地测量流体模型的动力学信息,可用于临床血流定量测量研究。
Objective：To investigate the selection of velocity encoding（Venc） and encoding direction with phase-contrast 3.0T MR imaging（3.0T PC-MRI） using a flow phantom,and to assess the accuracy and stability of the quantitative measurement of hydrokinetics.Methods：Firstly,holding the values of flow velocity and Venc,fluid dynamic information under different encoding directions were examined.Secondly,holding the values of Venc and encoding direction,the flow velocities measured by PC-MRI under different flow rates（0～5ml/s） were compared with standard flow velocities.Paired sample t test was employed to assess their statistical differences.Results：The direction of proton flow could only be correctly detected by selecting the encoding directions as SLICE or SI.Providing the value of Venc was appropriately greater than the actual flow velocity,no significant differences were existed between the measurements of flow velocity of PC-MRI with different flow rates and the corresponding actual flow velocities（t=-0.861,P=0.405）,a significant positive correlation（r=0.999,P〈0.001） was existed.Conclusion：Selecting a correct values of Venc and encoding direction is the premise of accurate measurement of hydrokinetics,3.0T PC-MRI proved to be an accurate and objective technique in providing the dynamic information of the flow phantom study and could be used in the clinical quantitative study of blood flow.
出处
《放射学实践》
北大核心
2010年第5期474-477,共4页
Radiologic Practice
基金
广东省科技攻关基金资助项目(2006B36030026)
广州市科技攻关基金资助项目(2006Z3-E0241)
关键词
定量测量
磁共振成像
血液动力学
模型
结构
Quantitative measurement
Magnetic resonance imaging
Hemodynamics
Models
structural
