摘要
目的总结分析变态反应性支气管肺曲霉菌病(ABPA)的临床特点,做到早期诊断和治疗。方法回顾性分析上海中山医院2006-2009年住院的ABPA患者临床资料。结果 ABPA患者共20例,确诊ABPA之前误诊为肺结核、普通肺炎各6例;比较常见的症状为咳嗽(100.0%)、咳痰(90.0%)、喘息(70.0%)、发热(55.0%)、咳痰栓(40.0%);胸部CT检查常见的病变为斑片状渗出影(95.0%),中心型支气管扩张(65.0%),黏液栓(25.0%),条索影和结节影(25.0%),肺门纵膈淋巴结肿大(25.0%)。结论 ABPA临床表现缺乏明显的特异性,极易被误诊和漏诊;提高对ABPA的认识,对可疑患者早期进行外周血嗜酸性粒细胞数、血清总IgE、烟曲霉菌抗原皮内试验,烟曲霉菌特异性IgE、支气管镜检查等以确诊。
OBJECTIVE To describe the clinical characteristics of allergic bronchopulmonary aspergillosis（ABPA）. METHODS The clinical data of 20 ABPA patients hospitalized in Zhongshan Hospital from 2006 to 2009 were retrospectively analyzed. RESULTS There were 20 cases with a mean age of（49.3± 17.3）years. Tuberculosis and pneumonia were initially misdiagnosed in 6 cases respectively. Common symptoms were cough, expectoration, wheeze, fever, chest tightness and sputum plug. Most lesions on chest CT were pathy infiltrations, central bronchiectasis, mediastinal and hilar lymphadenopathy, nodular opacities, mucoid impaetion. CONCLUSIONS The clinical symptoms of ABPA are nonspecific and the recognition of this disorder isn＇t enough, which cause ABPA misdiagnosis frequently. Measurement of peripheral blood eosinophilia, serum IgE level, A. fumigatus-specific IgE level and immediate cutaneous reaction to A. fumigatus are helpful to confirm the diagnosis.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第12期1708-1709,共2页
Chinese Journal of Nosocomiology
