摘要
目的:探讨贲门癌手术式选择对术后食管反流情况、临床症状及生存期的影响。方法:选取研究对象269例,其中T(total gastrectomy)组106例采用全胃切除术,P(proximal gastrectomy)组163例采近端胃切除术用,术后半年至一年复诊胃镜观察食管下端、贲门区有无胆汁黄染及食道下段有无粘膜糜烂。总结5年生存率,并对术后并发症的发生率和病死率进行对照分析。结果:胃镜病理检查结果显示:实验组食管胃吻合口的炎症反应比对照组轻(P<0.05),本组患者术后总的5年生存率为40.12%,其中T组为44.7%;P组为37.2%,经统计学处理,两组5生存率差异具有显著性意义(P<0.05)。结论:相对近端胃切除术全胃切除术的术后生存质量明显有优势,5年生存率也较高。
Objective：To investigate the enfluences of reflux esophagitis and life span after gastrectomy for the treatment of cancer of the cardia and stomach fundus.Methods：The clinical of 269 patients with cancer of cardia and stomach funds were analyzed retrospectively from 2000 to 2004.106 patients were treated using total gastrectomy（T group）,and 163 patients using proximal gastrectomy（P group）.The survival rates,postoperative complication rate,mortality and the inflammatory reaction of the tissue obtained at the esophagogastric junction using fl fiber gastroscope was observed.Results：The biopsy study of the esophagogastric junction showed that the inflammatory reaction in T group was slighter than that in P group（P 0.05）.The 5 year survival rates of group T were 44.7 % %,of group P were 37.2%,and the difference was statistically significant（P 0.05）.There was no significant difference between the two groups in the postoperative complication rate and mortality rate（P 0.005）.Conclusions：To patients with carcinoma of the gastric fundus and cardia,the postoperative complication rate and mortality rate should not be increased and the reflux esophagitis should be avoided by using total gastrectomy compared with proximal gastrectomy.
出处
《现代生物医学进展》
CAS
2010年第8期1520-1521,共2页
Progress in Modern Biomedicine
关键词
贲门癌
全胃切除术
返流性食管炎
Carcinoma of gastric cardia
Total gastrectomy
Reflux esophagitis
