期刊文献+

6426例高血压住院患者的增龄性变化和并存疾病分析 被引量:22

Clinical analysis of ageing changes and comorbidities in 6426 inpatients with hypertension
原文传递
导出
摘要 目的探讨高血压与年龄及并存疾病的关系。方法对我院2005年5月至2009年5月住院的6426例高血压患者的临床资料进行回顾性分析,按年龄分为青年组(18~44岁)312例、中年组(45~59岁)1529例、老年组(60~79岁)3847例及高龄组(80~99岁)738例,分析高血压患者占同年龄组住院患者的比例及并存疾病情况。结果6426例高血压患者中,男3438例(53.50),女2988例(46.5%);年龄18~99岁,平均(66.3±12.1)岁,其中青年组312例(4.8%),中年组1529例(23.8%),老年组3847例(59.9%),高龄组738例(11.5%);同期18岁以上住院患者共25504例,其中青年组11208例,中年组5389例,老年组7596例,高龄组1311例。高血压患者占同年龄组住院患者的比例依次为2.78%、28.37%、50.65%及56.30;青、中年组高血压患者比例男性明显高于女性,而老年组及高龄组男、女比例差异无统计学意义;6426例高血压患者并存糖尿病2069例(32.2%),高脂血症1508例(23.50),睡眠呼吸暂停综合征105例(1.6%),冠心病1061例(16.5%),心功能不全904例(14.1%),脑卒中2353例(36.6%),肾功能不全678例(10.6%)。结论高血压患病率随增龄而增加。高血压尤其是老年高血压其相关危险因素有群集现象,糖尿病、高脂血症、睡眠呼吸暂停综合征等相关疾病既是高血压发病的危险因素,同时又加重了高血压对心、脑、肾等重要靶器官的损害,而引起严重的心脑血管事件。因此,高血压治疗除积极降压达标外,应加强综合治疗以防止或延缓并发症的发生。 Objective To discuss the relationship of hypertension with ageing and comorbidities in 6426 inpatients. Methods The data of 6426 inpatients with hypertension from May 2005 to May 2009 were analyzed retrospectively. All inpatients were divided into four groups: the young-aged group from 18 to 44 yrs (n=312, 4.8%), the middle-aged group from 45 to 59 yrs (n=1529, 23.8%), the elderly group from 60 to 79 yrs (n=3847, 59.9%) and the old old group from 80 to 99 yrs (n= 738, 11.5 % ). The percentages of hypertension patients in the same age group over the same period were calculated and the comorbidities were observed respectively. Results Of 6426 hypertensive cases, there were 3438 males (53.5%) and 2988 females (46.5%), ranging from 18 to 99 yrs with the average age of (66.3± 12.1) yrs. There were 25 504 inpatients over 18 years old including 11 208 in the youth group, 5389 in the middle-aged group, 7596 in the elderly group and 1311 in the old old group. The proportions of hypertension inpatients to total in-patients in the four age groups were 2.8%, 28.4%, 50.7% and 56.3% respectively. In the youth and middle-aged groups, numbers of males with hypertension were more than of females, however there was no significant difference in gender in the elderly and the old old groups. Within 6426 inpatients with hypertension, 2069 (32.2%) had diabetes mellitus, 1508 (23.5%) had hyperlipidemia, 105 (1.6%) had sleep apnea syndrome, 1061 (16.5%) had coronary artery disease, 904 (14.1%) had heart failure, 2353 (36.6%) had stroke and 678 (10.6%) had kidney failure. Conclusions The prevalence of hypertension increases with ageing significantly. The correlated risk factors for hypertension include diabetes mellitus, hyperlipidemia and sleep apnea syndrome, being a clustering phenomenon, especially for elder patients. These risk factors also deteriorate the damage on heart, brain, kidney and other target organs, which might ultimately result in serious cardio-cerebral vascular events. Therefore, besides control of blood pressure, we should strengthen the complex treatment on hypertension to prevent and delay the occur of complicating diseases.
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2010年第5期355-358,共4页 Chinese Journal of Geriatrics
关键词 高血压 危险因素 年龄因素 Hypertension Risk factors Age factors
  • 相关文献

参考文献13

  • 1中华人民共和国卫生部高血压联盟(中国).中国高血压防治指南.2005年修正版.
  • 2王文,马丽媛,刘明波,邓卿,张宇清,李卫,朱鼎良,林曙光,黄峻,刘力生.初始低剂量氨氯地平加替米沙坦或复方阿米洛利联合治疗对高血压患者血压控制率影响的阶段报告[J].中华心血管病杂志,2009,37(8):701-707. 被引量:89
  • 3Stampfer MJ,Colditz GA.Estrogen replacement therapy and coronary heart disease:a quantitative assessment of the epidemiologic evidence.Int J Epidemiol,2004,33:445-453.
  • 4张秀荣,史立宏,李雪莲,刘跃春,康白.三羟异黄酮降低去卵巢大鼠外周血炎性因子和动脉张力[J].中华高血压杂志,2009,17(9):835-839. 被引量:2
  • 5王薇,赵冬.中国老年人高血压的流行病学[J].中华老年医学杂志,2005,24(4):246-247. 被引量:174
  • 6Gu D,Gupta A,Muntner P,et al.Prevalence of cardiovascular disease resk factor clustering among the adult population of China:results from the International Collaborative Study of Cardiovascular Disease in Asia (Inter Asia).Circulation,2005,112:658-665.
  • 7Chinali M,Devereux RB,Howard BV,et al.Comparison of cardiac structure and function in American Indians with and without the metabolic syndrome(the Strong Heart Study).Am J Cardiol,2004,93:40-44.
  • 8郭志荣,胡晓抒,武鸣,周明浩,周正元.血脂与高血压关系的前瞻陛研究[J].中华流行病学杂志,2009,30(6):554-558. 被引量:26
  • 9Tsioufis C,Thomopoulos K,Dimitriadis K.The incremental effect of obstructive sleep apnea syndrome on arterial stiffness in newly diagnosed essential hypertensive subjects.J Hypertens,2007,25:141-146.
  • 10Young T,Peppard PE.Epidemiology of obstructive sleep apena a population health perspective.Am J Respir Crit Care Med,2002,165:1217-1239.

二级参考文献41

  • 1刘力生.2004年中国高血压防治指南(实用本)[J].中华心血管病杂志,2004,32(12):1060-1064. 被引量:2611
  • 2杨新颖,朱哲蓓,刘跃春,高尔.三羟异黄酮对去势雌性大鼠主动脉壁NF-κB的表达影响[J].中国病理生理杂志,2005,21(10):1950-1953. 被引量:3
  • 3武阳丰,梁立荣.高血压是代谢综合征中的一个组分吗?[J].中华流行病学杂志,2006,27(12):1020-1022. 被引量:3
  • 4中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量:5235
  • 5Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. JAMA, 2003, 289: 2560-2572.
  • 6Sesso HD, Buring JE, Chown M J, et al. A prospective study of plasma lipid levels and hypertension in women. Arch Intern Med, 2005,165: 2420-2427.
  • 7Haperin RD, Sesso HD, Ma J, et al. Dyslipidemia and the risk of incident hypertension in men. Hypertension, 2006,47: 45-50.
  • 8Haffner SM, Ferrannini E, Hazuda HP, et al. Clustering of cardiovascular risk factors in confirmed prehypertensive individuals. Hypertension, 1992,20: 38-45.
  • 9Haffner SM, Miettinen H, Gaskill SP, et al. Metabolic precursors of hypertension: the San Antonio Heart Study. Arch intern Med, 1996,156:1994-2000.
  • 10Skarfors ET, LitheU HO, Selinus I. Risk factors for the development of hypentension: a 10-year longitudinal study in middle-aged men. J Hypertens, 1991,9:217-232.

共引文献287

同被引文献138

引证文献22

二级引证文献221

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部