摘要
本文对４５例高危新生儿采用含中／长链脂肪乳剂（ＭＣＴ／ＬＣＴ）的肠道外营养（ｔｏｔａｌｐａｒｅｎｔｅｒａｌ ｎｕｔｒｉｔｉｏｎ，ＴＰＮ），并与给予一般支持疗法的３０例高危新生儿作对照。结果发现试验组体重尤其是早产儿、极低出生体重儿的体重增速显著、并发症少；试验组与对照组血清胆红素均出现明显下降，且下降速度相近；两组治疗前后碱性磷酸酶的比较及两组高胆儿治疗前后血清胆红素的比较均无显著性差异；两组治疗前后 ＡＬＴ、ＡＳＴ、ＳＧＰＴ均在正常范围，出院后一个月随访未发现肝功能异常，说明对高危新生儿实施舍ＭＣＴ／ＬＣＴ的 ＴＰＮ能更好地促进生长发育。含ＭＣＴ／ＬＣＴ的ＴＰＮ，对新生儿的肝胆功能影响较小，中／长链脂肪乳剂优于单纯长链脂肪乳剂。
This paper has reported 45 high risk neonates experimentally treated by total parenteral nutrition (TPN) and 30 controlly treated by supporting treatment, which the TPN include middle and long chain fat emulsions (MCT/LCT). The result showed the nenoatal weight especial in premature infants and very low birth weight infants increased sig- nificantly and there were less complications in the experimental group. The serum bilirubin in the experimental group and in the control group obviously fell and the descending amplitude of the two groups were concordant. there were no significant difference of serum alka- line phosphatase and serum bilirubin between before treatment and after treatment in two groups The ALT、AST and SGPT were in the range of normal value between before treatment and after treatment. These results indicate that the MCT/LCT could accelerate the growth and development of the high risk nenoates and didn't almost affect liver and binary tract function of these neonates, so the MCT/LCT was more dominant than the smiple long chain fat emulsions.
出处
《新生儿科杂志》
1999年第1期4-7,共4页
The Journal of Neonatology
