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酶联免疫斑点技术诊断潜伏结核的系统分析 被引量：2

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摘要 目的系统分析方法评价酶联免疫斑点技术快速诊断潜伏结核的准确性。方法通过检索PubMed、EMBASE、CNKI等数据库和其他方式收集文献。用Meta-Disc软件计算合并灵敏度、合并特异性和ROC曲线等评价T细胞斑点试验的诊断正确性。结果终纳入6篇文献。酶联免疫斑点技术在检测潜伏结核时,均显示了较高的灵敏度,但特异性相对较低,且存在异质性。合并灵敏度=93.9%[95%CI(90.9%-96.2%)],合并特异性=合并SPE为66.2%[95%CI(62.4%-69.8%)],ROC曲线下面积为0.9658。结论联免疫斑点技术诊断潜伏结核显示了较高的灵敏度,但特异性相对较差,限制了该方法的应用。
作者 邹俊辉 陶小华 关杨 肖祖克
机构地区 南昌大学研究生院医学部 深圳市慢性病防治中心 江西省人民医院呼吸科
出处 《中国实用医药》 2010年第15期100-102,共3页 China Practical Medicine
关键词 潜伏结核 分枝杆菌 诊断 酶联免疫斑点技术 系统分析
分类号 R446.6 [医药卫生—诊断学]
  • 相关文献

参考文献17

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二级参考文献11

  • 1乐军,梁莉,李苏辉,张跃建,肖和平.酶联免疫斑点试验快速诊断结核分枝杆菌感染的临床应用价值[J].中华检验医学杂志,2006,29(11):1005-1008. 被引量：70
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  • 10肺结核诊断和治疗指南[J].中华结核和呼吸杂志,2001,24(2):70-74. 被引量：2918

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中国实用医药
2010年 第15期

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