摘要
目的评价静脉滴注甲基强的松龙(intra venousmethyl prednisolone’IVMP)冲击疗法治疗急性视神经炎(acute optic neuritis’AON)的临床疗效并对相关因素进行分析研究。方法回顾性分析我院2007～2009年住院86例(132眼)患者的临床资料。结果①IVMP治疗后患者的视力、视野、眼底、视觉诱发电位均有不同程度的改善(P<0.01);②IVMP的疗效受年龄,就诊时机,就诊时视力等因素的影响,性别及脑脊液检查结果与疗效之间无相关性。头部MRI无病灶者疗效好。结论大剂量IVMP治疗急性视神经炎合理有效。
Objective To investigate the clinical effect of intravenous high dose methylprednisolone in acute optic neuritis and the factors that influence the effect of this therapy.Methods 86 cases hospitalized in 2008～2009 were analysed.Results ①VA’optic disc’visual field and PVEP were improved in different degree after treatment of IVMP and the difference had marked significance（respectively P〈0.01）.②IVMP efficacy affected by age, treatment timing, treatment, and many other factors when the impact of visual.Conclusion IVMP is reasonable and effective for AON.
出处
《中国实用医药》
2010年第15期85-86,共2页
China Practical Medicine
关键词
甲基强的松龙
视神经炎
临床研究
intravenous methylprednisolone
acute optic neuritis
clinical study
