摘要
目的研究格拉诺赛特（Ｇｒａｎｏｃｙｔｅ－ＣｏｌｏｎｙＳｔｉｍｕｌａｔｉｎｇＦａｃｔｏｒ，Ｇ－ＣＳＦ）既粒细胞集落刺激因子在化疗中对白细胞的作用。方法观察两组共５７例病人。Ａ组：２６例患者，第一周期化疗后，当白细胞低于２．０×１０９时，予以Ｇ－ＣＳＦ治疗。第二周期则为停化疗药２４小时后应用Ｇ－ＣＳＦ。自身对照，观察白细胞的恢复情况。Ｂ组：３１例患者，７９个周期中分别于白细胞＜３．０×１０９，＜２．０×１０９，＜１．０×１０９时予以Ｇ－ＣＳＦ治疗。结果Ａ组：停化疗法２４小时予以Ｇ－ＣＳＦ治疗有效且经济。Ｂ组：白细胞＜３．０×１０９时应用Ｇ－ＣＳＦ最有效及经济。结论Ｇ－ＣＳＦ升白细胞的作用是确切有效的。
Objective To study the Granocyte stimulating effects of Granocyte (G CSF) during chemotherapy. Methods Fifty seven patients were observed. For 26 patients in group A after first cycle chemotherapy,G CSF was given with WBC less than 2.0×10 9/L,In the second cycle after chemotherapy 24 hours G CSF was given. For 31 patients in group B G CSF was given with WBC<3.0×10 9,<2.0×10 9,<1.0×10 9 individually. Result In Group A G CSF was given after 24 hours chemotherapy that was effective and economic.In Group B that G CSF was given with WBC <3.0×10 was effective. Conclusion G CSF has remarkable effect on chemotherapy induced leucocytopenia.
出处
《中国肿瘤临床与康复》
1999年第1期37-38,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
