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中国九个人群耵聍的遗传多态性 被引量:14

GENETIC POLYMORPHISM OF CERUMEN IN NINE POPULATIONS OF CHINA
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摘要 报道了九个人群的耵聍位点基因。计算表明中国各族人群在耵聍位点上的遗传分化程度非常大,固定指数F_(ST)=0.22。本文根据耵聍基因频率在我国和邻近地区的分布趋势,认为亚洲东北地区应是干型基因的起源地,目前世界上耵聍位点基因频率分布格局主要是基因扩散的结果,而非选择作用造成的。 The distribution of cerumen types in seven ethnic groups, as well as Han nationality from two different regions, was examined on total 1571 subjects. The gene frequency of dry cerumen in Mongolian (Inner Mongolia) is 0.9323; Hani (Yunnan) 0.8091; Jingpo (Yunnan) 0.7769; Dai (Yunnan) 0.7071; Achang (Yunnan) 0.6810; Deang (Yunnan) 0.5928; Buyi (Guizhou) 0.6834; Han (Inner Mongolia) 0.9817 and Han (Fujian) 0.8971. The genetic differentiation among the populations in China was studied using data on cerumen dimorphism in different Chinese ethnic groups collected from available sources. The fixation index Fst is equal to 0.22, which indicates an extremely great differentiation in cerumen gene frequencies when compared with those of other loci. The distribution of dry cerumen gene frequency on the world shows that some populations in northeast Asia, including Han in North China, have the highest gene frequency and it declines in all directions to other regions. It suggests that the dry cerumen gene was originated by a mutation in northeast Asia long long ago when Mongoloid was just formed and today's distribution of cerumen gene frequency in the world is mainly a result of gene diffusion rather than that of salection.
出处 《人类学学报》 CSCD 北大核心 1990年第3期236-243,共8页 Acta Anthropologica Sinica
关键词 人类群体遗传 耵聍 基因频率 Cerumen Gene frequency Human population genetics
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参考文献4

  • 1崔东生,中华耳鼻咽喉科杂志,1986年,21卷,70页
  • 2张振标,人类学学报,1982年,1卷,53页
  • 3方惠泰,中华耳鼻咽喉科杂志,1982年,17卷,195页
  • 4罗克梁,辽宁中级医刊,1981年,6期,46页

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