摘要
研究脑梗死患者血细胞流变学、红细胞膜流动性、变形性、血小板活化聚集、胆固醇结晶及循环内凝团块含量与脑梗死的病理关系。采用美国布氏多功能显微镜的活血分析法，在高放大倍数[1．5万倍]下直接观察红细胞、血小板、胆固醇结晶及活性血栓的细胞流变学情况及变形性。研究表明两组相比有明显的差异性，红细胞呈串珠样改变，其变形能力差、膜流性减低（P＜0．05），血粘度高，血小板聚集率增高，循环内凝块增多，两组相比P＜0．01。血流变学改变、红细胞串珠样改变、红细胞膜变形性减低、血小板聚集率增高，血浆粘度及流动栓子增多是脑梗死发病的重要病理基础。临床上应对血液成分进行积极研究和探讨，为缺血性脑血管病的预防、诊断、治疗以及预后判断等，提供重要的资料及实际意义。
To study the blood cell hemoyheology, the mobility and deformability of red cell membrane, activity and as-sembly of platelets, the content of cholesterol crvstals and thrombus in circulation in cerebral infarction patientrs. Observing thecell hemorheological condition of the red cell, platelet, cholesterol cryitals, and active thrombus in active blood analysis withBradford's microscope (15,000 times) .The study indicates that in the ceredral infarction patients, the red cell appearedrowleax and its deformbility was poor and its membrane mobility reduced (P < 0.05). In this group blood viscosity was higher,the platelet assembling rate rose and the thrombus in circulation increases more significantly than the nomal group (P < 0.01).The change of membrane mobility, the raising of platelet assemble rate, the in creasing of plasma viscosity and flowing embolismare the important pathological basis of cerebral infarction . It may provide important material and practical meaning for preclud-ing, diagnosing, curing and prognosising ischmia cerebralvascular diseases.
出处
《河南实用神经疾病杂志》
1999年第1期5-7,共3页
Henan Journal of Practical Nervous Diseases
