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血清CYFRA21-1、NSE联合检测在肺癌临床诊断中的意义

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摘要 目的:探讨电化学发光免疫分析技术(ECLIA)联合检测血清中NSE和CYFRA21-1在肺癌诊断中的临床意义。方法:用ECLIA法检测105例肺癌患者,36例肺良性疾病患者血清NSE和CYFRA21-1水平。结果:与肺良性疾病组相比,肺癌患者血清中NSE和CYFRA21-1水平明显升高(p<0.05),两项标志物联合检测的水平和敏感性与肺癌病理类型有关。NSE和CYFRA21-1的敏感性分别为38.1%和59.5%,特异性分别为86.1%和91.6%。两项标志物联合检测的敏感性、特异性、准确性分别为73.3%、88.9%和77.3%。结论:血清CYFRA2121、NSE联合检测在肺癌早期诊断及病情检测方面具有比较重要的临床价值,两者联合检测有明显的互补性,可明显提高肺癌诊断的敏感性。
作者 徐荡 朱润庆
出处 《中国民族民间医药》 2010年第9期83-83,89,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
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