摘要
目的 分析 Ａｓｋｉｎ 瘤临床病理特征，为该肿瘤的诊断与治疗提供依据。方法 对６ 例 Ａｓｋｉｎ 瘤组织常规处理， Ｈ Ｅ、 Ｐ Ａ Ｓ、网状纤维染色。结果 临床上为青少年胸肺部肿块伴疼痛，生存期短，预后差，２ 年生存率３３ ％ ，５ 年生存率为０ 。组织学上以稀少的纤维血管间质将小圆、卵圆瘤细胞围绕成巢状或小叶状结构。网染细胞间网状纤维少或无， Ｐ Ａ Ｓ染色部分病例（ ＋ ） 。结论 Ａｓｋｉｎ 瘤为一种位于胸肺部神经内分泌源性的高度恶性肿瘤，临床病理与胸壁外尤文瘤、原始神经外胚瘤比较无显著性意义。
Objective To provide the clinicopathological features of Askin tumor for its bases of diagnosis and treatment. Methods 6 cases of Askin tumor samples were studied with general paraffin section, HE, PAS, reticular fiber staining. Results Clinically, the tumor was often seen in young patients with painful thoracopulmonary masses. The prognosis was bad, and its survival rates of two and five years being 38% and 0% respectively. The nest-like or lobular structures composed of small round-to-oval cells were surrounded by sparse fibrovascular stroma. Among tumor cells there were no or few resticular fibers, however in the surrounding of tumor masses the fibers were found. The tumor in a part of cases was positive for PAS. Conclusions Askin tumor is a high malignant neurosecretory tumor in thoracopulmonary region. Clinicopathologically, the tumor has no significant difference from Ewing tumor located outside the thoracic wall and primitive neuroectodermal tumor.
出处
《诊断病理学杂志》
CSCD
1999年第1期25-26,共2页
Chinese Journal of Diagnostic Pathology
