摘要
先证者，男，39岁，反复发作的口腔、生殖器溃疡10年，腰、背、位关节明显设疼，弯腰、转体、行走困难6年，脚背部毛囊炎样皮损3年，间断发热半年。腰椎CT片示骨质增生和椎间隙变窄。HLA-B27（＋）。针刺反应（＋）。其一、二级亲属中另有不同程度的强直性脊柱炎患者5位，均不伴有白塞氏病。本家系调查提示，不仅强直性脊椎炎具有明显遗传倾向．而且决定强直性脊椎炎和白塞氏病的基因位点，具有一定相互关联。
The proband, 39-year-old man had repeated oral and geital ulcers for almost 10 years, lumbocral pain and akinesia for 6 year, folicullitis on chest and back for 3 years, interval fever for half a years. Lumbar vetebrae CT shew hyperosteogeny and narrowed interspaces HIA-B27 positive. Acupuncture test positive. There were 5 patients with ankylosing spondylitis in his 1stand 2nd grade relatives. This report indicated not only ankylosing spondylitis had genetic predisposion, but the situs determined ankylosing spondylitis and Behcet's disease may have relationship each other.
出处
《中国优生与遗传杂志》
1999年第1期102-102,104,共2页
Chinese Journal of Birth Health & Heredity
关键词
强直性脊椎炎
家系
白塞氏综合征
并发症
Behcet's disease, disease Ankylosing spondylitis Hereditary family line
