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RNA干扰在脑胶质瘤分子靶标研究中的进展 被引量：5

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摘要 脑胶质瘤是神经外科中最常见的神经肿瘤,发病率约占颅内肿瘤的44.69%,其中恶性胶质瘤占70%[1-2],目前标准的治疗方法是最大限度地进行手术切除,并结合放、化疗和其他治疗方式。但由于胶质瘤存在恶性增殖和侵袭性强的特点,手术很难完全切除,且术后极易复发．如何控制胶质瘤的恶性增殖和侵袭是目前研究的焦点。胶质瘤化、放疗的效果也不满意，胶质母细胞瘤患者中位生存期仅12～15个月。
作者 徐涛 陈菊祥 卢亦成
机构地区 第二军医大学附属长征医院神经外科上海市神经外科研究所
出处 《实用医学杂志》 CAS 北大核心 2010年第8期1443-1445,共3页 The Journal of Practical Medicine
基金 国家863高科技计划项目(编号:2007AA02Z483) 国家自然科学基金项目(编号:30772247)
关键词 脑胶质瘤 RNA干扰 分子靶标 胶质母细胞瘤 手术切除 恶性增殖 中位生存期 神经肿瘤
分类号 R739.4 [医药卫生—肿瘤]
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参考文献20

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共引文献5

同被引文献50

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实用医学杂志
2010年 第8期

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