摘要
通过人工土壤法,研究0.1,1,10,100,1000μg/kg类二噁多氯联苯暴露浓度对赤子爱胜蚓(Eisenia fetida)抗氧化酶(SOD酶、CAT酶和GST酶)、抗氧化分子(GSH)、氧化损伤物(MDA)等生理活性指标在第2,7,14,28d时的影响.结果显示,类二噁多氯联苯刺激赤子爱胜蚓生理活性显著增加(P<0.05),可诱导蚯蚓抗氧化系统应答启动;不同暴露时间下,受试物浓度与蚯蚓生理活性的相关性分析显示,蚯蚓不同生理活性指标对受试物的最佳响应时间不同,Cu-ZnSOD响应最早(7d),SOD,CAT,GSH,MDA次之(14d),GST响应最迟(28d);在最佳响应时间下,受试物暴露浓度对数与生理活性值对数均存在显著的剂量-效应关系(P<0.001)
Using artificial soil test,physiological activities in earthworms （Eisenia foetida）,which included superoxide dismutase （SOD,Cu-Zn SOD）,catalase （CAT） and gulathione-S-transferase （GST）,and other biochemical activities,such as GSH and MDA,exposed to dioxin-like PCBs at the levels of 0.1,1,10,100,1000μg/kg,were observed after 2,7,14 and 28d exposure.Dioxin-like PCBs could significantly increase SOD,Cu-Zn SOD,CAT,GST activities and GSH and MDA levels （P0.05）,and induce starting of antioxidant systems in the earthworms.The relationships results showed that the best response times of various physiological activities in earthworms to dioxin-like PCBs were different.The best response time of Cu-Zn SOD activities was 7 days,whereas that of GST activities was 28 days.The best response times of others physiological activities were all 14 days.During the best response times,there were significantly dose-response relationships between the dioxin-like concentrations logarithms and physiological activities logarithms （P0.001）.
出处
《中国环境科学》
EI
CAS
CSCD
北大核心
2010年第5期699-704,共6页
China Environmental Science
基金
国家自然科学基金资助项目(20040432005)
中央级公益性科研院所2009年基本科研业务专项
关键词
类二噁多氯联苯
赤子爱胜蚓
人工土壤
生理活性
剂量-效应
dioxin-like PCBs
earthworm （Eisenia fetida）
artificial soil
physiological activities
dose-response
