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开郁健脾法对脾虚大鼠血清胃泌素、尿D-木糖影响的实验研究 被引量:13

Experimental study of effects of relieving stagnation-syndrome and invigorating spleen method on serum gastrin,urine D-xylose in insufficiency of the spleen rats
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摘要 目的观察具有开郁健脾功效中药复方对脾虚大鼠体质量、血清胃泌素、尿D-木糖排泄率的影响。方法以破气苦降加饥饱失常的方法建立脾虚证大鼠模型,随机分组,实验组中药复方煎剂灌胃,以ELISA法测定大鼠血清胃泌素,间苯三酚法测定D-木糖排泄率。结果 (1)与模型组比较,中药复方低、中、高剂量组体质量明显增长(P<0.01)。(2)与模型组比较,中药复方低、高剂量组、中剂量组尿D-木糖排泄率显著增高(P<0.05、P<0.01)。结论开郁健脾中药复方有促进胃肠吸收的作用。 Objective To observe the effects of relieving stagnauon-syndrome ana invigoraung spleen method to weight, serum gastrin, urine D-xylose in insufficiency of the spleen rats. Methods The insufficiency of the spleen rats model was estabhshed by break down and fill gas bitter bunger method. 40 rats were divided into 5 groups, and the experimental groups were given herbal decoction, determined serum gastrin by ELISA, urine D-xylose excrete rats by phloroglucinol method. Results (1) The weight in low, middle and high group were increased obviously than the model group( P 〈 0.01 ). (2)The urine D-xylose in low, high and middle group were added than the model group ( P 〈 0.05 or P 〈 0.01 ). Conclusion Relieving stagnation-syndrome and invigorating spleen herbs have the effect that promote stomach and intestine absorption.
作者 呼延和 张君
出处 《中医儿科杂志》 2010年第3期12-16,共5页 Journal of Pediatrics of Traditional Chinese Medicine
关键词 小儿厌食 血清胃泌素 尿D-木糖排泄率 开郁健脾 中药复方 children anorexia serum gastrin urine D-xylose relieving stagnation-syndrome and invig- orating spleen herbal decoction
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