摘要
钛种植体表面的多孔形貌对其生物活性有很大的影响。本研究采用化学和电化学方法在钛表面制备出不同纳米管径的微/纳米结构层,再分别对其进行仿生矿化和模拟体液与小牛血清白蛋白(BSA)共沉积实验,考察不同纳米管径的微/纳米结构对材料表面的生物活性的影响。利用扫描电子显微镜、X射线衍射仪等进行分析测试。结果表明,微/纳米结构化钛表面的生物活性随着纳米管径的增大而增强;BSA的加入加速了矿化,同时降低了羟基磷灰石涂层的结晶度。
Porous surfaces have an important effect on bioactivity of titanium implants.In this study,two micro/nanostructural titanium surfaces were prepared by chemical and electrochemical method.The two samples had different diameters of nanotubes.Tests of biomineralization and codeposition in simulated body fluid and bovine serum albumin（BSA） were carried out in order to evaluate the bioactivity of micro/nanostructural titanium surfaces.The information of the surfaces was detected using scanning electron microscope and X-ray diffractometer.The results showed that the bioactivity of micro/nanostructural titanium increased with the diameter of nanotubes.Furthermore,the existence of BSA can accelerate biomineralization and decrease the crystallinity of hydroxyapatite coating.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2010年第2期320-323,共4页
Journal of Biomedical Engineering
基金
国家大学生创新性实验计划项目资助(西南交通大学2007-3)
国家自然科学基金资助项目(50871093)
关键词
钛
纳米管径
微/纳米结构
生物活性
Titanium
Nano-diameter
Micro/nanostructure
Bioactivity
