摘要
维持性血液透析(血透)患者乙型肝炎病毒(HBV)感染率明显高于健康人群和慢性肾脏病非透析患者。透析患者HBV感染症状多较轻微但易出现慢性化进展,针对此类病例抗病毒治疗依然是关键。本文重点就抗病毒药物核苷(酸)类似物用于血透患者合并乙型肝炎治疗作一综述。
Incidence of hepatitis B virus （HBV） infection is much higher in maintenance hemodialysis （HD）patients than that in healthy controls or other chronic kidney disease patients who do not need HD. Maintenance HD patients tend to be mild in symptoms but more progressed to chronic hepatitis. Therefore, antiviral therapy still is a major consideration. This review summarizes the application of nucleoside and nucleotide analogues for HBV infection in HD patients.
出处
《世界临床药物》
CAS
2010年第5期271-275,共5页
World Clinical Drug
关键词
核苷(酸)类似物
血液透析
乙型肝炎病毒
nucleoside analogues
nucleotide analogues
hemodialysis
hepatitis B virus
