摘要
我们用自制DFY-I型超声图像定量分析诊断仪对6只犬正常、缺血及再灌注过程中超声心动图局部心肌组织回声平均灰阶(GS)值、分贝(dB)值及其心动周期变异幅度(CVGS和CVdB)进行了动态定量分析,并同时测量室壁厚度和收缩期增厚率的变化.结果发现:冠脉阻断后20分钟,缺血区GS、dB值增高(GS:80.17±4.45vs88.00±6.57);dB:27. 17±1.72vs29.00±2.28 p均<0.05), CVGS、CVdB值降低(GS:16.83±2.32vs3.33±2.25:dB:6.00±0.89vs1.17±0.41 P均<0.05),同时室壁变薄(6.45±0.46mmvs5.87±0.47mmp<0.05).收缩期增厚率降低(55.78±6.10%vs7.88±1.84% p<0.05).再灌注后10分钟,GS、dB值和室壁厚度均恢复正常(P=NS).CVGS、CvdB值的恢复过程则相对缓慢,并与室壁收缩期增厚率的恢复同步且密切相关(r=0. 81.P<0.05).结论:急性心肌缺血时,缺血区GS、dB值增高,CVGS、CvdB值降低;CVGS、CvdB值的变化与心肌组织的收缩力密切相关,通过定量分析超声心动图心肌组织回声强度变化不但能区别正常与缺血心肌,同时可评估心肌组织的收缩功能.与国外学者所测背向散射积分结果一致.
The values of mean grey steps (GS) , decible (dB) and their magnitude of cyclic varization (CVGS, CVdB) were measured in 6 oper chest dogs before, after 20 Min of coronary occlusion and followed by peperfusion at selected intervals with quantitative analysis system type DFY- I . The wall thickness and wall thickening were also measured at the same time. The results showed that after 20 Min of coronary occlusion, Gs and dB increased (GS : 80.17 ± 4.45vs88.00 ± 6.57 and dB : 27.17 ± 1.72vs29.00 ± 2.28, P<0.05 respectively) . CVGS and CVdB decreased (GS: 16.83 ± 2.23vs 3.33 ± 2.25 and dB : 6.00 ± 0.89vsl.l7 ± 0.41, P<0.05, respectively) . wall thickness decreased from 6.45 ± 0.46mm to 5.87 ±0.47mm (P<0.05) and wall thickening decreased from approximately 55.78 ? 6.10% to 7.88 ? 1.84 (P<0.05) . 10 Min after reperfusion. GL. dB and wall chickness recovered to basline values(P=NS respectively) , CVGS, CVdB and wall thickening recovered slowly and The changes of CVGS and CVdB corelated well with the changes of wall thickening (r=0.8091 P<0.05) . Conclusion: GS and dBincreas, CVGS and CVdB decreas when acute ischemia. CVGS and CVdB corelated well with the contractile function of regional myocardium. We can not only distinguish ischemia from nomal myocardium. But also can assess its contractility by quantitative analysis of echo intensity on two-dimentiolay echocardiographic images.
出处
《临床超声医学杂志》
1998年第4期226-229,共4页
Journal of Clinical Ultrasound in Medicine
关键词
超声组织定征
回声强度
超声心动图
心肌缺血
Ultrasonic tissue characterization Intensity quantitative analysis Inschemia and reperfusion
