期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

毛细管电泳手性拆分方法的研发策略 被引量：2

Research strategy of chiral separation by capillary electrophoresis
暂未订购
导出
摘要 本文总结了毛细管电泳手性拆分的基本策略、分离条件选择策略、环糊精体系的选择,并提出毛细管电泳手性拆分方法的一般研究与开发策略,可为以后的毛细管电泳手性分离分析提供借鉴与思路。 The selection method of separation condition and cyclodextrin and strategy of chiral separation by capillary electrophoresis were summarized,and a general research and development strategy was proposed,which can provide basis for chiral separation by capillary electrophoresis.
作者 陈伟成 刘长海 张海 朱臻宇 赵亮 张国庆 柴逸峰
机构地区 上海市南汇区中心医院药剂科 第二军医大学药学院药物分析教研室 第二军医大学东方肝胆外科医院药材科
出处 《药学实践杂志》 CAS 2010年第2期130-133,共4页 Journal of Pharmaceutical Practice
关键词 毛细管电泳 手性拆分 研发策略 capillary electrophoresis chiral separation research strategy
分类号 R917 [医药卫生—药物分析学]
  • 相关文献

参考文献13

  • 1Jimidar MI,Van Ael W,Van Nyen P,et al.A screening strategy for the development of enantiomeric separation methods in capillary electrophoresis[J].Electrophoresis,2004,25(16):2772.
  • 2宫守凤,何新亚,林炳承.毛细管电泳手性拆分中的二元环糊精体系[J].化学进展,2001,13(6):450-454. 被引量：4
  • 3Cucinotta V,Giuffrida A,Maccarrone G,et al.The 6-derivative of beta-cyclodextrin with succinic acid:a new chiral selector for CD-EKC[J].J Pharm Biomed Anal,2005,37(5):1009.
  • 4Salami M,Jira T,Otto HH.Capillary electrophoretic separation of enantiomers of amino acids and amino acid derivatives using crown ether and cyclodextrin[J].Pharmazie,2005,60(3):181.
  • 5Yang WC,Yu AM,Yu XD,et al.Modeling and optimization of the chiral selectivity of basic analytes in chiral capillary electrophoresis with negatively charged cyclodextrins using electrochemical detection[J].Electrophoresis,2001,22(10):2025.
  • 6Wistuba D,Schurig V.Recent progress in enantiomer separation by capillary electrochromatography[J].Electrophoresis,2000,21(18):4136.
  • 7Daali Y,Cherkaoui S,Christen P,et al.Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin[J].Electrophoresis,1999,20(17):3424.
  • 8Rizzi AM,Kremser L.pKa shift-associated effects in enantioseparations by cyclodextrin-mediated capillary zone electrophoresis[J].Electrophoresis,1999,20(13):2715.
  • 9Fillet M,Chankvetadze B,Crommen J,et al.Designed combination of chiral selectors for adjustment of enantioseparation selectivity in capillary electrophoresis[J].Electrophoresis,1999,20(13):2691.
  • 10Varesio E,Gauvrit JY,Longeray R,et al.Central composite design in the chiral analysis of amphetamines by capillary electrophoresis[J].Electrophoresis,1997,18(6):931.

二级参考文献6

  • 1[5]Eric Peyrin,Yves Claude Guillaume.J Chromatogr A,1999,849:563
  • 2[6]Siouffi A M,R Phan-Tan-Luu.J Chromatogr A,2000,892:75
  • 3[7]Victoria L McGuffin,Marina FM Tavares.Anal Chem,1997,69:152
  • 4[8]Schlabach T D,Excoffier J L.J Chromatogr,1988,439:173
  • 5[10]Marcone AL de Oliveira,Guostavo A Micke,Roy E Bruns,Marina FMTavares. J Chromatogr A,2001,924:533
  • 6朱晓峰,林炳承.毛细管电泳测定主客分子相互作用的结合常数[J].分析化学,1999,27(12):1408-1411. 被引量：6

共引文献5

同被引文献22

  • 1汪永忠.伏立康唑对映体的手性高效液相色谱分离[J].中国药师,2006,9(3):231-232. 被引量：5
  • 2朱静.伏立康唑的药理特性及临床应用[J].天津药学,2007,19(4):48-50. 被引量：15
  • 3Williams ML, Wainer IW. Role of chiral chromatography in ther- apeutic drug monitoring and in clinical and forensic toxicology [J].TherDrugMonit, 2002, 24(2): 290.
  • 4Soudijn W, Van Wijngaarden I, Ijzerman AP. Stereoselectivity of drug-receptor interactions[J].Drugs, 2003, 6 ( 1 ) : 43.
  • 5Wang X, Zeng S. Stereoselective metabolic and pharmacokinetic analysis of the chiral active components from herbal medicines [J]. Curr Pharm Anal, 2010, 6(1) : 39.
  • 6Ekiert RJ, Krzek J, Talik P. Chromatographic and electrophoret- ic techniques used in the analysis of triazolc antifungal agents-a review [ J ]. Talanta, 2010, 82 (4) : 1090.
  • 7Hassan YA, Imran A. Comparative study of the enantiomerie res- olution of chiral antifungal drugs econazole, miconazole and sul- conazole by HPLC on various cellulose chiral colmnns in normal phase mode[J]. JPharm Biomed Anal. 2002. 27(3-4), 441.
  • 8Hamdy DA, Brocks DR. A stereospecific high-performance liquid chromatographic assay for the determination of ketoconazole enanti- omers in rat plasma[ J ]. Biomed Chromatogr, 2008, 22 (5) : 542.
  • 9Castro-Puyana M, Crego AL, Marina ML. Enantiomefic separation of ketoconazole and terconazole antifungals by electrokinetie chromatog- raphy: Rapid quantitative analysis of ketoconazole in pharmaceutical formulations [ J ]. Electrophoresis, 2005, 26(20) : 3960.
  • 10Castro-Puyana M, Crego AL, Marina ML. Separation and quanti- tation of the four stereoisomers of itraconazole in pharmaceutical formulations by electrokinetic chromatography [ J ]. Electrophore- sis, 2006, 27(4) : 887.

引证文献2

药学实践杂志
2010年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部