摘要
目的探讨急性期脑卒中患者入院时平均动脉压(MAP)与其住院期间死亡、残疾危险性之间的关系。方法回顾性分析2003-01-2005-12内蒙古通辽市6家医院的3938例脑卒中患者的入院血压、血脂、血糖、疾病史以及住院期间死亡和残疾资料,采用Logistic回归模型,对入院血压与急性脑卒中患者住院期间死亡和残疾的关系进行统计分析,计算OR和95%CI。结果在出血性脑卒中患者中,调整了年龄、性别、民族、吸烟、饮酒、血脂和血糖因素后,与MAP<103 mm Hg者相比,MAP≥133 mm Hg者的死亡OR值为2.12,MAP在103～116、117～132和MAP≥133 mm Hg者的残疾OR值分别为1.85、2.15和1.99(均P<0.01)。在缺血性脑卒中患者中,各组的死亡和残疾的OR均无统计学意义。结论急性出血性脑卒中患者入院时MAP越高,其发生死亡和残疾的危险性越大。
Objective To explore the role of admission mean arterial pressure（MAP） on the risk of death in-hospital and disability in acute ischemic and hemorrhagic stroke patients.Methods Observational study of 3938 patients with comfirmed stroke admitted in six hospitals in Tongliao city,Nei Mongol,from 1 January,2003 to 30 December,2005,with retrospective analysis of blood pressure,plasma lipid and plasma glucose,history and outcome.Results In multivariate logistic regress,by optimal modification of age,gender,race/ethnicity,cigarette smoking and alcohol,higher MAP（MAP≥133 mm Hg） in hemorrhagic stroke patients has an association with hospital mortality（OR 2.12） compared to those with MAP〈103 mm Hg.Also,MAP of 103-116,117-132 and ≥133 mm Hg was associated with disability with OR 1.85,2.15 and 1.99,respectively.However,there was no significant difference of death and disability among groups in ischemic stroke patients（all P〉0.05）.Conclusion Hemorrhagic stroke patients with elevated MAP on admission lead to higher risk of hospital mortality and disability.
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2010年第4期339-343,共5页
Chinese Journal of Hypertension
关键词
平均动脉压
脑卒中
死亡
残疾
Mean arterial pressure
Stroke
Mortality
Disability
