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白癜风与黑素瘤关系的研究进展 被引量：4

Advance on Relationship between Vitiligo and Melanoma
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摘要 白癜风是以皮肤黑素细胞破坏导致的获得性色素脱失性疾病;黑素瘤是皮肤、黏膜黑素细胞异常增生导致的一种恶性肿瘤。近年来研究发现黑素瘤患者的白癜风发生率远远高出正常人群,这一现象的发生可能是机体抗黑素瘤的细胞及体液免疫应答作用于正常黑素细胞的结果。 Vitiligo is a skin disease that is caused by destruction of melanocytes and is characterized by acquired depigmentation.Malignant melanoma is a malignant tumor caused by abnormal proliferation of melanocytes.Recent studies found that malignant melanoma patients have a far higher vitiligo incidence than normal population,which may be a consequence that the cellular and humoral immune response against malignant melanoma act on the normal melanocytes.
作者 牛建荣 赵广
机构地区 解放军空军总医院皮肤科
出处 《中国皮肤性病学杂志》 CAS 北大核心 2010年第4期371-372,375,共3页 The Chinese Journal of Dermatovenereology
关键词 白癜风 黑素瘤 免疫应答 Vitiligo Melanoma Immune response
分类号 R758.41 [医药卫生—皮肤病学与性病学]
  • 相关文献

参考文献20

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二级参考文献42

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共引文献34

同被引文献53

  • 1周峻伟,姚卫海,郭玉红,王和天,周爱国,张红升,范圣凯,陈冰璞.从肝论治白癜风病因病机浅析[J].实用中医内科杂志,2009,23(10):6-7. 被引量：10
  • 2徐建华,邱仞之.热休克蛋白的研究进展及生物学意义[J].海军医学杂志,1997,15(3):268-272. 被引量：1
  • 3王忠,王伟深,邹兴梅,廖祖苑.白癜风与肺结核病免疫相关性研究[J].岭南皮肤性病科杂志,2004,11(3):216-217. 被引量：2
  • 4杨壮群,荔鹏,屠军波,王正辉,虎小毅,张铁良.TNF-α与放线菌酮协同作用促体外培养黑素细胞凋亡的实验研究[J].中华整形外科杂志,2005,21(4):302-305. 被引量：4
  • 5LADDHA N C, DWIVEDI M, MANSURI M S, et al. Vitiligo: in- terplay between oxidative stress and immune system[ J]. Exp Der- matol, 2013, 22(4): 245 -250.
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  • 7KROLL T M, BOMMIASAMY H, BOISSY R E, et al. 4 - Tertia- ry butyl phenol exposure sensitizes human melanocytes to dendritic cell- mediated killing: relevance to vitiligo[ J]. J Invest Derma- tol, 2005, 124(4): 798-806.
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  • 9ABDOU A G, MARAEE A H, REYAD W. Immunohistochemical expression of heat shock protein 70 in vitiligo [ J ]. Ann Diagn Pathol, 2013, 17(3) : 245 -249.
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引证文献4

二级引证文献14

中国皮肤性病学杂志
2010年 第4期

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