窄谱中波紫外线对人脐静脉内皮细胞的作用机制研究
摘要
银屑病最先发生的病理改变是血管的分布和形成的改变。血管内皮生长因子(VEGF)是众多血管生成因子中效力最强、作用最关键的特异性调控因子。血管内皮细胞产生的基质金属蛋白酶(MMP)在血管发生、形成和再生中具有重要意义。窄谱中波紫外线(NB—UVB)(波峰311nm)治疗银屑病具有很好的疗效和安全性^[1]。
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2010年第4期278-280,共3页
Chinese Journal of Dermatology
参考文献8
-
1Krutmann J,Morita A.Mechanisms of ultraviolet(UV)B and UVA phototherapy.J Investig Dermatol Symp Proc,1999,4(1):70-72.
-
2Cho TH,Lee JW,Lee MH,et al.Evaluating the cytotoxic doses of narrowband and broadband UVB in human keratinocytes,melanocytes,and fibroblasts.Photodermatol Photoimmunol Photomed,2008,24(3):110-114.
-
3李福民,王雪,段西凌,宋林红,董丹丹,董巍,何迅,应川蓬.窄谱中波紫外线对寻常性银屑病血管调节因子的作用机制研究[J].中华皮肤科杂志,2009,42(3):163-166. 被引量:7
-
4陆星显,岑岭,郭盛华,倪诚.窄谱UVB治疗寻常型银屑病及其对血管内皮生长因子的影响[J].中国麻风皮肤病杂志,2007,23(1):73-73. 被引量:7
-
5Akman A,Dicle O,Yilmaz F,et al.Discrepant levels of vascular endothelial growth factor in psoriasis patients treated with PUVA,Re-PUVA and narrow-band UVB.Photodermatol Photoimmunol Photomed,2008,24(3):123-127.
-
6Fleischmajer R,Kuroda K,Hazan R,et al.Basement membrane alterations in psoriasis are accompanied by epidermal over expression of MMP-2 and its inhibitor TIMP-2.J Invest Dermatol,2000,115(5):771-777.
-
7Choi CP,Kim YI,Lee JW,et al.The effect of narrowband ultraviolet B on the expression of matrix metalloproteinase-1,transforming growth factor-betal and type Ⅰ collagen in human skin fibroblasts.Clin Exp Dermatol,2007,32(2):180-185.
-
8Zucker S,Mirza H,Conner CE,et al.Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells:conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation.Int J Cancer,1998,75(5):780-786.
二级参考文献15
-
1温炬,罗权,张锡宝,林中方.阿维A治疗前后对银屑病患者血管内皮生长因子表达的影响[J].中华皮肤科杂志,2005,38(9):540-542. 被引量:6
-
2陈琴芳,杨夕芳,陈昆,常宝珠,顾恒.窄谱中波紫外线治疗寻常性银屑病[J].中华皮肤科杂志,2005,38(10):646-647. 被引量:17
-
3Hem S, Mortimer PS. In vivo quantification of microvessels in clinically uninvolved psoriatic skin and in normal skin. Br J Dermatol, 2007, 156(6): 1224-1229.
-
4Hem S, Stanton AW, Mellor RH, et al. In vivo quantification of the structural abnormalities in psoriatic microvessels before and after pulsed dye laser treatment. Br J Dermatol, 2005, 152(3 ): 505-511.
-
5Neufeld G, Cohen T, Gengrinovitch S, et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J, 1999, 13( 1 ): 9-22.
-
6Simonetti O, Lucarini G, Goteri G, et al. VEGF is likely a key factor in the link between inflammation and angiogenesis in psoriasis: results of an immunohistochemical study. Int J lmmunopathol Pharmacol, 2006, 19(4): 751-760.
-
7陆星显,郭盛华,倪诚,关乃富,岑岭.窄谱中波紫外线对银屑病患者皮损中微血管密度和血清血管内皮生长因子水平的影响[J].皮肤病与性病,2007,29(3):10-12. 被引量:4
-
8Marks R, Barton SP, Shuttleworth D, et al. Assessment of disease progress in psoriasis. Arch Dermatol 1989;125:235- 240.
-
9van Weelden H, De La Faille HB, Young E, et al. A new development in UVB phototherapy of psoriasis. Br J Dermatol 1998;119:11 - 19.
-
10Walters IB, Buraek LH, Coven TR, et al. Suberythemogenic narrow- band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris. J Am Acad Dermatol 1999;40:893-900.
共引文献12
-
1穆震,邱静,乔锰.NB-UVB治疗银屑病的机制[J].中国医学文摘(皮肤科学),2009,26(3):156-158. 被引量:9
-
2王琳,陈金.窄谱中波紫外线在皮肤科的应用进展[J].实用医院临床杂志,2010,7(3):112-114. 被引量:11
-
3梁俊琴,刘玉琴,普雄明.NB-UVB治疗前后银屑病皮损中VEGF与CD106的表达[J].中国麻风皮肤病杂志,2010,26(9):631-633. 被引量:1
-
4吴满平,蒋惠平,王雪萍,钱利兴,金刚石.复方氟米松软膏合紫外线治疗结节性痒疹疗效观察[J].浙江中西医结合杂志,2011,21(11):803-804. 被引量:5
-
5潘政,张羽文.窄谱中波紫外线治疗寻常性银屑病疗效观察[J].国际皮肤性病学杂志,2012,38(1):59-59. 被引量:3
-
6范文葛,陶晓瑜,王玲,魏梅.白芍总苷胶囊联合窄谱中波紫外线治疗寻常性银屑病[J].中华皮肤科杂志,2012,45(10):755-756. 被引量:9
-
7卢凤艳,荀皓,尹逊国,余妍欣.窄谱UVB治疗慢性单纯性苔藓和慢性肥厚性湿疹的临床疗效观察[J].昆明医科大学学报,2013,34(2):113-116.
-
8王吉松.窄谱UVB治疗慢性单纯性苔藓和慢性肥厚性湿疹的临床疗效观察[J].中国医药指南,2014,12(1):31-32. 被引量:3
-
9于葆华,谢勇,盛国荣.退银汤联合NB-UVB治疗寻常性银屑病的临床研究[J].时珍国医国药,2014,25(1):125-127. 被引量:7
-
10何春峰,吴爱萍,张丽,龙朝钦,杨桂兰,孙燕丽,杜华,张安方.白芍总苷联合窄谱中波紫外线及卡泊三醇治疗中度寻常性银屑病78例疗效分析[J].中国皮肤性病学杂志,2014,28(8):873-875. 被引量:13
-
1陈积愫,郑敏.银屑病与血管生成因子[J].国外医学(皮肤性病学分册),2000,26(1):13-16. 被引量:5
-
2张思瑶.荨麻疹[J].中国实用乡村医生杂志,2007,14(4):7-8.
-
3李萍,李建红,刘建中,冯进云,崔荣,刘启文.结合珠蛋白对特应性皮炎患儿外周血单一核细胞产生IFN-γ和IL-4细胞因子的影响[J].中华皮肤科杂志,2009,42(9):640-641.
-
4郑双进,黎兆军.血管内皮生长因子及其在增生性皮肤病中的表达[J].医学综述,2010,16(2):194-197. 被引量:1
-
5汤伟.浅谈荨麻疹的中医治疗[J].医学信息(下旬刊),2010(2):144-144. 被引量:1
-
6张晓梅,李鸣九,梁智江,邱梦桃,赵艳阳.润燥止痒胶囊联合小剂量依匹斯汀治疗慢性荨麻疹的疗效观察[J].湖北中医杂志,2014,36(7):41-42. 被引量:6
-
7江一.冬季哪些人最容易得冻疮[J].中华养生保健,2005,0(11):54-54.
-
8张瑞丽,王千秋.梅毒螺旋体膜蛋白 Tpp17体外活化血管内皮细胞的实验研究[J].中华微生物学和免疫学杂志,2013,33(11):807-812. 被引量:1
-
9荨麻疹[J].中国医学文摘(皮肤科学),1999,0(6):344-344.
-
10李彩云,李小艳.面部糖皮质激素依赖性皮炎[J].基层医学论坛,2010,14(20):648-649. 被引量:2