摘要
目的探讨不同血糖水平患者血液流变学各项指标变化的临床意义。方法通过检测30例确诊糖尿病患者、30例确诊糖耐量异常患者与30名正常人的血液流变学6项指标,分析其特点及临床意义。结果糖尿病患者的全血高切黏度、全血低切黏度、血浆黏度、血纤维蛋白原4项指标与正常对照组比较,有明显增高(P<0.05)。而红细胞压积及红细胞沉降率与正常对照组比较无明显变化(P>0.05)。结论糖尿病患者多伴有血液流变学的改变,且这种改变从糖耐量异常时即已发生,所以早期进行血液流变学检测,对预防糖尿病和控制其并发症的发生有重要意义。
Objective To probe the clinical significance of hemorheology changes in patients with different blood glucose levels. Methods By detecting six indicators of hemorrheology in 30 cases with diagnosed diabetes,30 cases with diagnosed impaired glucose tolerance and 30 cases with normal glucose tolerance, we analyzed their abnormalities and their clinical significance. Results The whole blood viscosity,plasma viscosity and plasma fibrinogen in the diabetes（DM） group and the impaired glucose toleranee（IGT） group were significantly higher than in normal control（NGT） group （P〈0. 05）. The Hematocrit and erythrocyte sedimentation rate showed no significant change （P〉0.05） in NGT versus DM and IGT group. Conclusions Diabetic patients have changes in blood rheology, and such a change occurrs from the time of impaired glucose tolerance. It is important to detect the changes in blood rheology for preventing diabetic complications.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2010年第4期267-269,共3页
Chinese Journal of Diabetes
基金
上海市卫生局科研基金(2007127)
关键词
糖尿病
糖耐量异常
血液流变学
Diabetes
Impaired glucose tolerance
Hemorheology
