摘要
目的探讨中青年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者与颈动脉及下肢动脉粥样硬化斑块之间的关系。方法将应用多导睡眠监测仪(PSG)诊断的110例OSAHS患者分成轻度组(36例)、中度组(38例)、重度组(36例),另设36名健康体检者作为对照组,所有入选者行颈动脉和下肢动脉彩色多普勒超声检测。结果OSAHS患者颈动脉和(或)下肢动脉粥样硬化斑块检出率明显高于对照组(P<0.01),且随着病情加重斑块的发生率有增加的趋势,而且在OSAHS各亚组间下肢动脉粥样硬化斑块的检出率显著高于颈动脉粥样硬化斑块检出率(P<0.01)。结论颈动脉和下肢动脉粥样硬化斑块与OSAHS密切相关,应引起高度重视。
Objective To study the relationship between the carotid,lower limb atherosclerotic plaques and obstructive sleep apnea-hypopnea syndrome（OSAHS）.Methods One hundred and ten patients with OSAHS were diagnosed using polysomnography（PSG） and then divided into mild（n=36）,moderate （n=38）,and severe OSAHS group（n=36）,thirty-six healthy subjects were selected as the control group,their carotid and lower limb artery were measured by color Doppler ultrasonography.Results The incidence of atherosclerotic plaques in OSAHS patients was obviously higher than control group（P〈0.01）,and was correlated with the severity.Moreover,the incidence of lower limb atherosclerotic plaques is significantly higher than that of carotid atherosclerotic plaques among three OSAHS groups（P〈0.01）.Conclusions The carotid and lower limb atherosclerotic plaques are closely associated with OSAHS,which should be paid more attention to.
出处
《卒中与神经疾病》
2010年第2期86-88,91,共4页
Stroke and Nervous Diseases
