摘要
目的对比分析中晚期肺癌支气管动脉灌注化疗(BAI)与全身静脉化疗的疗效。方法中晚期肺癌患者40例,均经病理证实,分为支气管动脉灌注化疗组(治疗组)与全身静脉化疗组(对照组)。结果治疗组和对照组近期疗效有效率分别为75%和40%,半年、1年、2年生存率分别为95%、85%、45%和80%、45%、10%,组间差异有统计学意义(P<0.05),而且在毒副反应方面治疗组明显低于对照组。结论支气管动脉灌注化疗是治疗中晚期肺癌的最有效方法之一,比全身静脉化疗能更有效地控制肺内原发病灶,延长患者的生存期,减轻患者的毒副反应。
Objective To compare the therapeutic effect of bronchial arterial infusion （BAI） and traditional vein chemotherapy in moderate - late carcinoma of lung. Methods Seventy - six patients with moderate - late carcinoma of lung were randomly treated by BAI （treatment group） or traditional vein chemotherapy （control group）. Results The response rates of primary lesion in Treatment group and control group were 75% and 40% , the survival rate at 6,12 and 24 months were 95% ,85% ,45% andS0% ,45% ,10% , moreover,Toxicity response in the treatment group was significantly lower than control group. They were different between the two groups （ P 〈 0. 05 ）. Conclusion BAI is one of the most effective therapies for the treatment of moderate - late carcinoma of lung and it can prolong patients＇survival. Compared with vein chemotherapy, BAI has better effect in control primary lesions and reduce toxicity
出处
《中国医学创新》
CAS
2010年第12期1-2,共2页
Medical Innovation of China
关键词
支气管肺癌
介入疗法
支气管动脉灌注
静脉化疗
Bronehogenic carcinoma
Interventional therapy
Bronchial arterial infusion
Vein chemotherapy
