摘要
目的探讨老年糖尿病(DM)合并高血压(HP)患者24 h脉压、心率变异性与靶器官损害的关系。方法对单纯老年DM合并HP患者95例,伴靶器官损害患者126例,对比分析24 h动态血压监测及心率变异性各指标。结果伴靶器官损害组与单纯老年DM合并HP患者组比较:24 h平均舒张压、日间舒张压、夜间舒张压降低,日间收缩压、夜间收缩压、24 h脉压、日间脉压、夜间脉压升高;心率变异性各指标(SDNN、SDANN、SD、rMSSD、PNN50)降低,两组比较,差异有显著性(P<0.01或P<0.05)。结论动态脉压及心率变异性的变化可反映老年DM合并HP患者靶器官损害程度。
Objective To study the correlation of 24h ambulatory pulse pressure（PP）,heart rate variability（HRV） and target organs damage（TOD） in patients of aged Diabetes with Hypertension.Method Twenty four hours ambulatory pulse pressure（PP） and heart rate variability（HRV） were monitored and compared with ambulatory blood pressure monitoring（ABPM） and Holter in 95 cases suffering from Diabetes with Hypertension and 126 cases suffering from MS and TOD. Result Compared with the patients with MS,the patients suffering from DM with HP had lower 24h mean diastolic pressure,day diastolic pressure and night diastolic pressure,higher day systolic pressure and night systolic pressure,24h PP,day PP and night PP and lower indexes of heart rate variability（SDNN,SDANN,SD,rMSSD,PNN50）.The difference between the two groups was significant（P〈0.01 or P〈0.05）. Conclusion Ambulatory pulse pressure and HRV can mirror the seriousness of DM with HP and higher ambulatory pulse pressure and lower HRV are the characteristics of patients with DM combined with HP target organs damage.
出处
《南华大学学报（医学版）》
2010年第1期101-103,共3页
Journal of Nanhua University(Medical Edition)
关键词
老年糖尿病
高血压
脉压
心率变异性
靶器官损害
aged Diabetes
hypertension
pulse pressure
heart rate variability
targets organ damage
