期刊文献+

反应停降低化疗消化道反应的研究

暂未订购
导出
摘要 目的 研究反应停在降低化疗消化道反应中的作用.方法 将40例肺癌患者随机分成2组,另外10例肺癌伴糖尿病患者设为糖尿病组;给予顺铂为基础的方案化疗,常规给予阿扎司琼+地塞米松基础止吐治疗的同时,实验组加反应停,对照组给予安慰剂,糖尿病组则给予阿扎司琼+安慰剂+反应停,观察消化道反应发生率.结果 实验组止吐有效率为96.2%;对照组止吐有效率87.5%;糖尿病组止吐有效率为85.0%.实验组与对照组有显著差异,糖尿病组与对照组无显著差异.结论 加用反应停能明显增强阿扎司琼+地塞米松的止吐效果,降低化疗病人消化道反应发生率,反应停加阿扎司琼能达到阿扎司琼+地塞米松的止吐效果.
作者 杜剑平
出处 《实用肿瘤学杂志》 CAS 2010年第2期172-174,共3页 Practical Oncology Journal
  • 相关文献

参考文献8

二级参考文献26

  • 1Hsueh-Erh Chiou,Tsang-En Wang,Ying-Yue Wang,Hui-Wen Liu.Efficacy and safety of thalidomide in patients with hepatocellular carcinoma[J].World Journal of Gastroenterology,2006,12(43):6955-6960. 被引量:21
  • 2[1]Wiser W,Berger A.Practical management of chemotherapy-induced nausea and vomiting.Oncology Williston Park),2005,19:637
  • 3[2]Aapro M,et al.Palonosetron is effective in preventing acute and delayed chemotherapy-induced nausea and vomiting in patients recieving highly emetogenic chemotherapy (HEC)[Abstract].Support Care Cancer,2003,11:A17
  • 4[3]Jordan K,Kasper C,Schmoll HJ.Chemotherapy-induced nausea and vomiting:Current and new standards in the antiemetic prophylaxis and treatment.Eur J Cancer,2005,41:199
  • 5[4]Roila F,Donati D,Tamberi S,et al.Delayed emesis:Incidence,pattern,prognostic factors and optimal treatment.Support Care Cancer,2002,10:88
  • 6[5]website:http//www.mascc.org.Multinational association for supportive care in cancer.Consensus Conference on antiemitic therapy Perugia,2004,March 29-31
  • 7[6]Hesketh PJ,Kris MG,Grunberg SM,et al.Proposal for classifying the acute emetogenicity of cancer chemotherapy.J Clin Oncol,1997,15:103
  • 8[7]Morrow GR.The effect of a susceptibility to motion sickness on the side effects of cancer chemotherapy.Cancer,1985,55:2766
  • 9[8]Osoba D,Zee B,Pater J,et al.Determinants of postchemotherapy nausea and vomiting in patients with cancer.Quality of Life and Symptom Control Committees of the National Cancer Institute of Canada Clinical Trials Group.J Clin Oncol,1997,15:116
  • 10[9]Doherty KM.Closing the gap in prophylactic antiemetic therapy:Patient factors in calculating the emetogenic potential of chemotherapy.Clin J Oncol Nurs,1999,3:113

共引文献219

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部