摘要
目的:综合分析体外受精—胚胎移植(invitro fertilization and embryotransfer,IVF-ET)后生化妊娠丢失及临床妊娠流产的影响因素。方法:收集2006～2008年行IVF-ET助孕治疗后妊娠的327例资料,根据其不同的妊娠结局分为A、B、C3组,对可能的影响因素进行回顾性分析,并比较3组在行IVF-ET治疗过程中的各种相关因素之间的差异。结果:单因素分析显示年龄、取卵日的子宫内膜厚度、HCG注射日的E2水平及有无排卵障碍在3组之间差异有统计学意义(P<0.05),Logis-tic回归分析表明年龄与妊娠成功率呈负相关,取卵日子宫内膜厚度及HCG注射日的E2水平与妊娠成功率呈正相关。结论:年龄、取卵日子宫内膜厚度、HCG注射日的E2水平是影响妊娠结局的主要因素,排卵障碍也是IVF-ET后导致不良妊娠结局的相关因素。
Objective： To analyze the effect factors of pregnancy loss and clinical abortion after in vitro fertilization and embryo transfer （IVF - ET） synthetically. Methods： The data of 327 pregnant cases after IVF - ET from 2006 to 2008 wre collected, then the cases were divided into group A, group 13 and group C, the potential effect factors were analyzed retrospectively, and the differences in the course of IVF - ET among related factors of the three groups were compared. Results ： There was significant difference in age, endometrial thickness on the day of ovum pick - up （ OPU）, serum concentration of estradiol on the day of human eborionie gonadotropin （HCG） and ovulation failure rate among the three groups （ P 〈 0. 05 ） . There was a negative correlation between age and success rate of pregnancy, and there was a positive correlation between endometrial thickness on the day of OPU, serum concentration of estradiol on the day of HCG and success rate of pregnancy. Conclusion ： The main effect factors of pregnancy outcomes include age, endometrial thickness on the day of OPU and serum concentration of estradiol on the day of HCG, ovulation failure is a related factor of adverse pregnancy outcomes after IVF - ET.
出处
《中国妇幼保健》
CAS
北大核心
2010年第13期1811-1814,共4页
Maternal and Child Health Care of China
