摘要
用原位杂交法观察了培养海马神经元中BDNFmRNA的表达，得出与他人报道略有不同的结果：上述种经元经KA处理后，BDNFmRNA表达增高不仅可经非NMDA受体介导，而且可通过谷氨酸的释放再间接活化NMDA受体．
The expression or BDNF mRNA in cultured hipPOcampal neurons was detected by in site hybridization. Our resultS was identical with other reports. besides one exception: the Increase of BDNF mRNAlevel caused by KA administration was not only mediated by non-NMDA glutamatf receptors but also belated indirectly by the release or glutamate subsequently activating NMDA receptors.
关键词
海马
神经元
谷氨酸受体
原位杂交
the expression of BDNF mRNA
cultured hippocampal neurons
glutamate receptors in situ hybridization
