摘要
目的探讨结节病复发的主要临床特点。方法将结节病复发定义为：结节病的临床和影像改变自发或经治疗完全缓解后，又出现结节病活动的证据并经影像学或病理证实。2004年至2008年在我院就诊的符合上述标准的结节病复发患者共12例，对上述患者的临床资料进行总结分析。结果12例中11例为女性，复发时间在缓解后4—38个月。12例结节病复发患者中10例在初治时接受了口服激素治疗，复发大多发生在激素减药过程中或停药早期，病情缓解超过3年复发的2例。3例在复发时有新发脏器受损。结论结节病复发主要发生在激素减量或停药早期，但也有病情稳定数年后复发，结节病患者应接受长期随访，并规范口服激素治疗方案，结节病复发时应进行全面检查，重新评估受累脏器。
Objective To study the main clinical characters of recurrent sarcoidosis. Methods Sarcoidosis recurrence were defined as presenting activity through imaging or histology after having self-relief or treated relief. There were 12 patients who consistent to the standard in all sarcoidosis patients from 2004 to 2008 in our hospital. Results All patients but one were male. The time of recurrent to the remission was from 4 to 38 months. 10 patients recei＇~ed oral steroid therapy. Recurrences often occurred in drug reducing or 6 months after drug withdrawal. There were 2 patients with recurrence time greater than 3 years after remission. Three patients presented new organ damages in recurrence. Conclusions The recurrence of sarcoidosis mostly occurred in the course of drug reduction or in the early stage of drug withdrawal and the recurrence time were hardly over 3 years after remission. The sarcoidosis patients must receive long time follow-up and the program of oral steroid therapy must be standardized.
出处
《中国综合临床》
2010年第5期516-518,共3页
Clinical Medicine of China
关键词
结节病
激素
复发
Sarcoidosis
Steroid
Recurrence
