摘要
目的：探讨老年患者肺部真菌感染的易患因素、临床特点及治疗转归情况。方法：采用回顾性方法，对2007年1月～2009年12月呼吸内科住院的62～78岁58例肺部真菌感染病例进行分析。结果：肺部真菌感染患者中，慢性阻塞性肺疾病48例（82．76％）。长期使用广谱抗生素32例（55．17％）、低蛋白血症24例（41．38％）、合并糖尿病18例（31．03％）是主要易患因素。药敏实验表明。病原菌以白色假丝酵母菌（86．21％）为主，抗真菌治疗痊愈43例（74．14％），好转8例（13．79％）。结论：老年患者肺部真菌感染无特异性的临床表现，基础疾病继发感染是肺部真菌感染的重要原因。白色假丝酵母茵是老年患者院内肺部真菌感染的主要致病菌，除有效的抗真菌治疗外，积极的综合治疗有助于提高真菌感染的治愈率。
Objective To investigate the influencing factors ,clinical features and treatment improvement condition on pulmonary fungal infection in aged patients. Method Total 58 cases of pulmonary fungal infection patients age 62 - 78 years hospitalized in respiratory medicine from January 2007 to December 2009 were analyzed with retrospective method. Results For 48 cases （82. 76% ） of chronic obstructive pulmonary disease,32 cases （55.17%） taking broadspectrum antibiotic for long time,24 cases （41.38%） of hypoproteinaemia and 18 cases （31.03%） associated diabetes were the vulnerable factors. Drug sensitive test indicated that the pathogenic bacteria gave priority to the Candida albicans （ 86, 21% ）. Forty - three cases （74. 14% ） were recovered by antifungal treatment and 8 cases （ 13.79% ） were improved. Conclusion There is no specific clinical feature in aged pulmonary fungal infection patients. The secondary infection of foundation sickness is the substantial clause on pulmonary fungal infection. The Candida alhicans is the main pathogen on pulmonary fungal infection in hospitalized aged patients. Besides the effective antifungal treatment,the active complex treatment is helpful to improve the cure rate of mycotic infection.
出处
《吉林医学》
CAS
2010年第13期1757-1759,共3页
Jilin Medical Journal
关键词
肺
老年
感染
真菌
Lung
Aged patients
Infection
Fungus
