摘要
气道重塑是除气道慢性炎症以外支气管哮喘的又一重要特征。近年来研究表明,Toll样受体可通过凋节多种致气道重塑因子如生长因子、细胞因子、炎性介质、趋化因子等的生成和活化,最终导致气道重塑。
Airway remodeling is another important feature of bronchial asthma except for chronic airway inflammation. Study shows that in recent years,Toll like receptors can regulate a variety of factors such as growth factors, cytokines, inflammatory mediators and so on, which induced airway remodeling production and activation, leading to airway remodeling Ultimately.
出处
《国际呼吸杂志》
2010年第3期154-158,共5页
International Journal of Respiration
基金
基金项目:国家自然科学基金(c03030203)
广西卫生厅课题(重200)
桂林市科学研究与技术开发计划课题(20080320~I)
广西青年科学基金(0991085)