摘要
目的了解山东省鲁北地区地方性氟中毒病情流行状况,进一步做好该病的防治工作。方法按照国家《地方病防治项目技术方案》的要求,于2008年对山东省鲁北地区的济阳、博兴、高青、广饶、武城、夏津、宁津等7县66个村的环境氟含量与地方性氟中毒病情流行情况进行了调查。结果7县66个村居民饮水含氟量有95.45%（63/66）的村超标,水氟含量（4.0 mg/L村24个（36.36%）,水氟含量最高村为5.80 mg/L。检测7县儿童即时尿氟含量879人份,平均几何均值3.49 mg/L,93.06%（818/879）个体尿氟水平超标,个体最大值21.02 mg/L。检查66个村8~12岁儿童氟斑牙2 579人,平均检出率73.52%,缺损率23.85%,氟斑牙指数1.76。临床检查16岁以上成人38 463例,氟骨症阳性检出率为4.78%（1 840/38 463）;X线摄片成人402例,X线氟骨症检出率为17.91%（72/402）,临床与X线氟骨症均以轻度为主。结论鲁北地区外环境水氟含量严重超标,氟中毒病情尚未得到有效控制,仍存在一定程度流行。
Objective To investigate the prevalence of endemic fluorosis in the north area of Shandong province,and to provide scientific basis for the prevention and control.Methods Sixty-six villages were randomly sampled for the study from 7 counties（Jiyang,Boxing,Gaoqing,Guangrao,Wucheng,Xiajin and Ningjin）in the north area of Shandong province.The concentration of environmental fluoride and the prevalence of endemic fluorosis were investigated with the National Technical Guidelines for Endemic Disease Control.Results 95.45%（63/66）of the villages had drinking water with fluoride concentration over national standard（1.0 mg/L）.Twenty-four villages had drinking water with fluoride concentration greater than 4.0 mg/L,including the maximum as 5.8 mg/L.The urinary fluoride concentration was tested in 879 children（aged 8-12 years）from 33 villages of the 7 counties.93.17%（818/879）of the tested children had higher concentration of urinary fluoride than normal range,with a maximum concentration as 21.02 mg/L.Dental fluorosis was confirmed in 73.52%（1 896/2 579）of the children with an average dental fluorosis index as 1.76.Dental damage was found in 23.85% of the children.The proportion of skeletal fluorosis was 4.78%（1 840/38 463）and 17.91%（72/402）with physical and X-ray examination,respectively.Conclusion The fluoride concentration of drinking water exceeds the national standard in most of the investigated villages in the north area of Shandong province.Additional efforts and resources have to be contributed for the prevention and control of the endemic fluorosis.
出处
《中国预防医学杂志》
CAS
2010年第4期332-335,共4页
Chinese Preventive Medicine
基金
中央补助地方公共卫生专项资金地方病防治项目(2007)
关键词
饮水
氟化物中毒
流行病学调查
Drinking water
Fluoride poisoning
Epidemiological investigation
