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大剂量静脉注射丙种球蛋白防治小儿川崎病冠状动脉病变临床疗效分析 被引量:8

Clinical Analysis on the Therapeutic Efficacy of High-dose Intravenous Immune Globulin in Coronary Artery Lesion Prevention and Cure for Children with Kawasaki Disease
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摘要 目的:探讨大剂量静脉注射丙种球蛋白(intravenous immune globulin IVIG)防治川崎病(Kawasaki disease KD)冠状动脉病变(coronary artery lesion CAL)的临床疗效。方法:将54例典型川崎病患儿随机分为观察组和对照组,对照组予以常规治疗,观察组在常规治疗的基础上予静脉注射丙种球蛋白,观察比较两组冠状动脉病变(coronary artery lesion CAL)恢复及发生情况。结果:观察组CAL恢复率高,且恢复期出现新发生的CAL率低于对照组。结论:大剂量IVIG能有效的防治CAL。 Objective :To investigate the therapeutic efficacy of high-dose Intravenous Immune Globulin (IVIG) in Coronary Artery Lesion (CAL) control of Kawasaki Disease (KD).Methods:54 cases of KD infants were randomly divided into investigated and contrast groups.The contrast group is given ordinary treatment,while the investigated group is given IVIG in addition.The recoveries and occurrences of CAL in these groups are observed and compared.Results:The investigated group has a higher CAL recovery rate,and the CAL recurrence rate is lower than the contrast group.Conclusion:High-dose IVIG is effective in CAL prevention and treatment.
出处 《医学信息(中旬刊)》 2010年第4期795-796,共2页 Medical Information Operations Sciences Fascicule
关键词 川崎病 IVIG CAL Kawasaki disease Intravenous immune globulin Coronary artery lesion
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