摘要
目的：研究和比较血清孕酮、β—HCG及雌二醇联合检测对异位妊娠的诊断价值。方法：收集40名异位妊娠及20名正常早孕的妇女，电化学发光法检测外周血孕酮、β-HCG及雌二醇水平。采用t检验、卡方检验及Logistic回归评价孕酮、β—HCG及雌二醇对异位妊娠的诊断价值。结果：异位妊娠组，孕酮、D—HCG及雌二醇分别是：326．3土132．2nmol／L，654．6±101．4UI／L和5102．6±1003．5pmol／L，正常早孕组则分别是：755．3±108．4nmol／L，6435．8±780．6UI／L和4982．6±1112．5pmol／L，异位妊娠组孕酮和0．HCG明显抵于正常早孕组（P〈0．05）。孕酮和β-HCG联合检测对异位妊娠诊断敏感性和特异性均明显高于其它检测组（P〈0．05）。Logistic回归提示较低水平孕酮和D．HCG对异位妊娠的诊断有预测价值。结论：联合检测孕酮和β—HCG可进一步提高异位妊娠诊断准确率，而雌二醇对异位妊娠无预测价值。
Objective：In order to investigate the diagnostic value of serum progesterone,β-HCG and estradiol on ectopic pregnancy.Method：We enrolled 40 ectopic pregnancy cases and 20 common early pregnancy cases,and to analyze progesterone,β-HCG and estradiol by electrochemical procedure.We evaluated the diagnostic value of the combination of progesterone,β-HCG and estradiol on ectopic pregnancy by t-test,chisquare-test,and Logistic regression.Result：Progesterone,β-HCG and estradiol in ectopic pregnancy group are 326.3±132.2nmol/L,654.6±101.4UI/L and 5102.6±1003.5pmol/L respectively, while 755.3± 108.4nmol/L,6435.8±780.6UUL and 4982.6±1112.5pmol/L in common early pregnancy group.Progesterone and β-HCG are significantly lower in ectopic pregnancy group compared with common early pregnancy group （P〈0.05）.The combination of progesterone and β-HCG has a higher diagnostic sensitivity and specificity on ectopic pregnancy （P〈0.05）.Lower level of progesterone and β-HCG has a higher diagnostic value on ectopic pregnancy by Logistic regression.Conclusion：The combination of progesterone and β-HCG can improve diagnostic accuracy on ectopic pregnancy whereas estradiol has no diagnostic value on ectopic pregnancy.
出处
《中医临床研究》
2010年第7期84-86,共3页
Clinical Journal Of Chinese Medicine
关键词
孕酮
Β-HCG
雌二醇
异位妊娠
早孕
Progesterone
β-HCG
Estradio
Ectopic pregnancy
early pregnancy
