摘要
目的探讨腹腔镜手术联合术中药物治疗异位妊娠对持续性异位妊娠(PEP)预防的疗效。方法回顾性分析我院收治114例异位妊娠患者,分为治疗组和对照组各57例。治疗组给于腹腔镜保守性手术联合术中药物治疗,对照组给于腹腔镜联合术后药物治疗,分别观察术后的PEP发生率。结果治疗组有1例发生PEP,发生率为1.75%;对照组有7例发生PEP,发生率为12.28%,差异具有统计学意义(P<0.05)。结论腹腔镜保守手术联合术中运用甲氨蝶呤治疗异位妊娠对预防PEP具有明显优势,是异位妊娠保守治疗中一种安全、可靠的方法。
Objective To evaluate the efficacy of combined treatment with laparoscopic conservative surgery and intraoperative methotrex- ate for the prevention of persistent ectopic pregnancy （ PEP）. Methods We retrospectively analyzed 114 cases of ectopic pregnancy treated in our hospital. The cases were divided into therapeutic group （57 cases） and control group （57 cases）. The patients in therapeutic group were treated with laparoscopic conservative surgery and intraoperativc chemotherapy; the patients in control group were treated with laparoscopic conservative surgery and postoperative chemothorapy. The incidence of postoperative persistent ectopic pregnancy in therapeutic group and control group was compared. Results Persistent ectopic pregnancy was observed in 1 case in therapeutic group （ 1.75% ）, while it was found in 7 cases in control group （ 12.28% ）. There was significant difference in the incidence of persistent ectopic pregnancy between the two groups （ P 〈 0.05 ）. Conclu- sion Laparoscopic conservative surgery combined with intraoperative methotrexate showed obvious advantages for preventing persistent ectopic pregnancy. It was a safe and reliable method for the treatment of ectopic pregnancy.
出处
《临床和实验医学杂志》
2010年第10期745-746,共2页
Journal of Clinical and Experimental Medicine
关键词
持续性异位妊娠
腹腔镜保守性手术
药物
Persistent ectopic pregnancy
Laparoscopic conservatve surgery
Chemotherapy
