摘要
利用还原型尼克酰胺腺嘌呤二核苷酸脱氢酶(NADPH-d)组织化学和核磷蛋白(FOS)免疫组织化学技术观察了一氧化氮合酶(NOS)在对牙齿加力刺激时三叉神经感觉核簇(Vcx)内的分布情况;NOS阳性结构与牙齿移动诱发的FOS蛋白表达之间的关系。结果表明,NOS阳性结构和FOS阳性神经元(FLN)在Vcx内的分布有一定的特点,两者之间又有重叠。表明NO参与了牙齿移动过程的中枢调控,进一步阐明了牙齿移动性刺激在中枢内的调控机制。
It was studied the central role of nitric oxide(NO) during experimental teeth movement and the relation between nitric oxide synthetase (NOS) positive neurons and FOS like immunoreactivity (FLN) with the NADPHdiaphorase histochemistry and immunocytochemical reaction method. Results indicated that NOS positive neurons and FLN showed typical distribution in Vcx and there was some overlap between them. It suggests that NO is involved in the central modulation of the stimulating message of teeth movement,and which further explains the central modulation mechanism of experimental teeth movement in rats.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1998年第2期127-128,131,I006,共3页
West China Journal of Stomatology
关键词
一氧化氮
Vcx
一氧化氮合酶
FOS基因
牙移动
\ nitric oxide\ \ nitric oxide synthetase\ \ FOSlike immunoreactivity neurons\ \ tooth movemnt