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NOS在大鼠Vcx内的分布及其与牙齿移动诱发FOS表达的关系

The Distribution of NOS in Vcx and Its Relation with the Expres sion of FOS Induced by Teeth Movement in Rats
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摘要 利用还原型尼克酰胺腺嘌呤二核苷酸脱氢酶(NADPH-d)组织化学和核磷蛋白(FOS)免疫组织化学技术观察了一氧化氮合酶(NOS)在对牙齿加力刺激时三叉神经感觉核簇(Vcx)内的分布情况;NOS阳性结构与牙齿移动诱发的FOS蛋白表达之间的关系。结果表明,NOS阳性结构和FOS阳性神经元(FLN)在Vcx内的分布有一定的特点,两者之间又有重叠。表明NO参与了牙齿移动过程的中枢调控,进一步阐明了牙齿移动性刺激在中枢内的调控机制。 It was studied the central role of nitric oxide(NO) during experimental teeth movement and the relation between nitric oxide synthetase (NOS) positive neurons and FOS like immunoreactivity (FLN) with the NADPHdiaphorase histochemistry and immunocytochemical reaction method. Results indicated that NOS positive neurons and FLN showed typical distribution in Vcx and there was some overlap between them. It suggests that NO is involved in the central modulation of the stimulating message of teeth movement,and which further explains the central modulation mechanism of experimental teeth movement in rats.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 1998年第2期127-128,131,I006,共3页 West China Journal of Stomatology
关键词 一氧化氮 Vcx 一氧化氮合酶 FOS基因 牙移动 \ nitric oxide\ \ nitric oxide synthetase\ \ FOSlike immunoreactivity neurons\ \ tooth movemnt
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