摘要
目的探讨脑钠素(BNP)水平与心功能的相关性,进一步说明BNP测定对心力衰竭(以下简称心衰)的重要性。方法随机选择56例住院心衰患者及52例无器质心脏病患者作为研究对象。入院当日采集血标本以备血浆BNP、血糖、血脂等检查,采用ELISA法测定血浆BNP水平,血浆BNP水平与心功能相关性采用SPSS10.0软件进行分析。结果随着心衰程度加重,血浆BNP水平逐渐升高,患者BNP降低值与左室射血分数(LVEF)存在良好负相关。结论CHF患者血浆BNP浓度升高,且随CHF程度的增加而显著升高。
Objective To explore the correlation of brain natriuretic peptide level with cardiac function in order to elucidate the importance of measurement of BNP in heart failure（HF）. Methods Fifty-six patients with heart failure and 52 patients controls without HF were enrolled in the study and samples of BNP,blood glucose and lipid were obtained on admission day.The plasma levels of BNP were examined by ELISA.The correlation of plasma levels of BNP with cardiac function were analyzed by SPSS for windows V10.0,statistical package.Results The plasma levels of BNP were gradually elevated with the severity of HF.The change of BNP level was negatively correlated with LVEF（P0.01）.Conclusion Plasma BNP levels increase in patients with CHF,and markedly increased according to the severity of heart failure classified by NYHA classification.
出处
《临床医学》
CAS
2010年第3期13-14,共2页
Clinical Medicine
关键词
心力衰竭
相关性
脑钠素
Heart failure
Correlation
Brain natriuretic peptide
