摘要
目的探讨终末期肾病(ESRD)患者血液透析过程中的并发症,尤其是对眼压的影响。方法采用病例对照研究。应用TOPCON非接触气压式眼压计对32例患者进行透析前及透析后的眼压测定,并用配对样本t检验进行分析比较。双眼间及性别间的比较采用两个独立样本t检验。透析前后眼压之间的关系采用直线相关分析。结果透析后眼压有所升高,有统计学意义(t=5.302,P<0.01),双眼间比较差异无统计学意义(t=0.604,P>0.05),性别间比较差异也无统计学意义(t=1.119,P>0.05)。透析后眼压与透析前眼压呈相关关系(r=0.669,P<0.01)。32例患者64眼中,透析后13只眼眼压下降,占20.31%,10只眼眼压平稳,占15.63%,41只眼眼压不同程度升高,占64.06%。结论血液透析可致眼压不同程度升高,采用有效的监测及预防措施可降低肾透析对患者视功能的损害。
Objective To study the complication of end -stage renal disease （ESRD） during hemodialysis , especially on the effects of intraocular pressure. Methods -The experimental design was case - control study. The intraocular pressure of 32 patients was measured before and after dialysis, and the results were analyzed by paired t -test. The comparison between left and right eyes and comparison between men and women were analyzed by two - sample t - test. The relation of intraocular pressure between before and after hemodialysis was analyzed by linear correlation. Results The intraocular pressure had a trend of increasing after dialysis, The statistical analysis showed that difference was significant （ t = 5. 302, P 〈 0.01 ）. There was no significant difference between left and right eyes （t =0. 604 ,P 〉 0.05 ）, and no significant difference between men and women as well（ t = 1. 119 ,P 〉0.05 ）. In 64 eyes of 32 cases, after dialysis , there were 13 eyes＇intraocular pressure reduced and accounted for 20.31% ;10 eyes kept smoothly and accounted for 15.63% ;41 eyes went up more or less accounted for 64.06% . Conclusion The effect of dialysis is related to intraocular pressure of patients at some degree. Effective observation and prevention may greatly reduce the damage of visual function of patients.
出处
《青海医学院学报》
CAS
2010年第1期63-66,共4页
Journal of Qinghai Medical College
关键词
血液透析
眼压
终末期肾病
Hemodialysis Intraocular pressure End -stage renal disease
