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大肠癌间质肥大细胞与恶性程度关系的研究

Mast cells in the stroma of large intestine carcinoma and its relationship to the malignant degree of carcinoma
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摘要 目的研究大肠癌间质肥大细胞与癌恶性程度的关系。方法:取35例大肠癌手术标本,经10%甲醛固定,高铁二胺/阿辛兰染色(HID/AB),用测微器计数每mm2肥大细胞平均数。结果大肠癌肥大细胞计数与癌恶性程度密切相关,恶性程度低组的肥大细胞计数显著多于恶程度高组(P<0.05)。结论大肠癌间质肥大细胞的计数作为判断肿瘤分化程度的参考数据有一定意义。 Objective In order to study the relationship between the number of mast cells in stroma of largeintestine careinoma and malignant degree of carcinoma. Methods 35 examples of large intestine carcinomawere fixed by 10% formaldehyde, stained by HID/AB and their number of mast cells counted at per squaremm. Results The number of mast cell in stromal of large intestine carcinoma is closely related to the malignantdegree of carcinoma, the number of mast cell in low malignant carcinoma group is significanhy more than thoseof in high malignant' group (p < 0.05 ). Conclusions Count in number of mast cells is a distinction ofjudging malignant degree of carcinoma.
出处 《合肥医学院学报》 1998年第A06期6-7,共2页 Journal of Zunyi Medical University
关键词 大肠癌 肥大细胞 高铁二胺 阿辛兰 癌变 large intestine carcinoma mast cell HID/AB
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  • 1丰艳,吴景兰,王一菱.大鼠肥大细胞异质性的免疫组织化学观察[J]河南医科大学学报,1996(01).
  • 2阎书凤.小鼠呼吸道肥大细胞的研究[J]山西医学院学报,1983(03).
  • 3D. Befus PhD,H. Fujimaki PhD,T. D. G. Lee PhD,M. Swieter PhD. Mast cell polymorphisms[J] 1988,Digestive Diseases and Sciences(3):16S~24S

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