摘要
国外基础研究认为钙拮抗剂异搏定可增加抗癌药长春新硷和阿霉素的细胞毒作用。根据该信息,本文用异搏定联合长春新硷、阿霉素组成“VOA”方案,对11例晚期癌症进行了第二期临床治疗研究,结果对晚期胃癌疗效最好,有效率达100％,其他癌也有较好的疗效,从而对晚期胃癌的临床治疗提供了一个较好的姑息性治疗方案。毒付作用不大,值得推广试用。同时在癌症临床治疗中采用钙拮抗剂配合化疗方面提供了一个先例。
The research abroa dindicates that calcium antagonist verap amil can increase the cytoto xicity action of ant icancer drugs VCR and ADM. Based on the information, this PaPer reports the results the clinical study of verapamil with VCR and ADM('VoA'scheme) in 11 cases of patients with late can cer. The results show that the effect is the best in patients with late stomachcancer allof cases. The effective rate is100％. some effects have obtained in the other cancer. This ma thod provides a good pallia tivescheme of treatment in patients with late stomach cancer and the side effect is not qui-te obvious. Thereby, it is significant to popularize.
出处
《青海医学院学报》
CAS
1990年第1期36-38,共3页
Journal of Qinghai Medical College
关键词
肿瘤
钙拮抗剂
异搏定
抗癌药
Keg words: Calcium Antagonist, Cancer Anficancer Drug
