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氩氦刀联合肝动脉化疗栓塞术治疗原发性肝癌的临床研究 被引量:7

Effect of cryotherapy by employing Argon/Helium subsequently combined with TACE on primary hepatic carcinoma
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摘要 目的:观察氩氦刀联合肝动脉化疗栓塞术治疗原发性肝癌的疗效。方法:40例原发性肝癌病人,根据病人情况选择TACE术和氩氦刀冷冻消融术治疗的先后顺序。1月后复查血清AFP、肝脏CT增强扫描及肝动脉造影(DSA)检查。随诊12个月。结果:治疗前AFP>400ng/ml,治疗后下降>50%者83.9%(26/31);肝脏CT增强扫描及DSA造影提示:肿瘤完全坏死50.0%(20/40);不完全坏死27.5%(11/40);部分坏死22.5%(8/40)。6个月、12个月生存率分别为91.0%和76%。治疗中、治疗后未发生严重并发症。结论:氩氦刀联合肝动脉化疗栓塞术治疗原发性肝癌疗效确切,不良作用少。 Objective:To investigate the effect of cryotherapy of employing Argon/Helium subsequently combined with TACE for primary hepatic carcinoma.Methods:Forty cases with primary hepatic carcinoma received cryotherapy of employing Argon/Helium subsequently combined with TACE.One month after the combined treatment,AFP(alpha-fetoprotein) and liver CECT(contrast enhancement computed tomography) and DSA were examined.The follow-up time was 12 months.Results:In 83.9% of patients with AFP level up to 400ng/ml,AFP value decreased more than 50%.Complete tumor necrosis was observed by liver CECT and DSA in 50.0%;incomplete necrosis in 27.5%;part necrosis in 22.5%.The 6-month and 12-month survival rates were 91.0% and 76.0% respectively without severe complications in the treatment.Conclusion:Subsequent combination of cryotherapy of employing Argon/Helium with TACE is an effective and safe therapy for primary hepatic carcinoma.
出处 《现代肿瘤医学》 CAS 2010年第4期757-759,共3页 Journal of Modern Oncology
关键词 氩氦刀 肝动脉化疗栓塞术 原发性肝癌 cryotherapy of employing Argon/Helium TACE primary hepatic carcinoma
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