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二期梅毒患者血清中IL-2、IL-10水平检测结果分析 被引量:3

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出处 《中国实验诊断学》 北大核心 2010年第4期596-597,共2页 Chinese Journal of Laboratory Diagnosis
基金 邯郸科技计划项目(0923108059-2)
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  • 1Cruz AR, Ramirez LG, Zuluaga AV, et al. Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartments [J/OL]. PLoS Negl Trop Dis, 2012, 6 (7): e1717 [2012-07-17]. http://www.plosntds.org/artiele/info% 3Adoi% 2F 10.1371%2Fjournal.pntd.0001717.
  • 2Cervantes JL, Dunham-Ems SM, La Vake CJ, et al. Phagosomal signaling by Borrelia burgdofferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8- mediated induction of IFN-beta [J]. Proc Natl Acad Sci U S A, 2011, 108(9): 3683-3688.
  • 3Fitzgerald TJ. The Thl/Th2-1ike switch in syphilitic infection: is it detrimemal? [ J ]. Infect Immun, 1992, 60 ( 9 ): 3475-3479.
  • 4Leader BT, Godomes C, VanVoorhis WC, et al. CD4+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis[J]. Infect Immun, 2007, 75(6): 3021-3026.
  • 5Carlson JA, Dabiri G, Cribier B, et al. The immunopathobiologyof syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity [J]. Am J Dermatopathol, 2011, 33(5): 433-460.
  • 6Zhao F, Wu Y, Zhang X, et al. Enhanced immune response and protective efficacy of a Treponema pallidum Tp92 DNA vaccine vectored by chitosan nanoparticles and adjuvanted with IL-2[J]. Hum Vaccin, 2011, 7(10): 1083-1089.
  • 7Podwifiska J, Zaba R, Chomik 1Vl, et al. The ability of periphera/ blood mononuclear cells (PBMC) of syphilitic patients to produce IL-2 [J]. FEMS Immunol Med Microbiol, 1995, 12(1): 17-27.
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  • 10Lazarus JJ, Meadows MJ, Lintner RE, et al. IL-10 deficiency promotes increased Borrelia burgdorferi clearance predominantly through enhanced innate immune responses [J]. J Immunol, 2006, 177(10): 7076-7085.

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