摘要
目的探索鉴别诊断良、恶性胸水和腹水性质有价值的实验室联合检测指标体系。方法采用放射免疫分析，对251例胸水和腹水中的甲胎蛋白（AFP）、癌胚抗原（CEA）、铁蛋白（Fer）、β2－微球蛋白（β2-MG）、绒毛膜促性腺激素（β-HCG）、铜蓝蛋白（CP）、透明质酸（HA）、层粘连蛋白（LN）进行了综合性检测。结果八项指标中Fer、LN、CEA、β-HCG、AFP在良、恶性胸水和腹水中有显著性差异（P＜0．01），此五项指标在恶性胸水和腹水中诊断阳性率依次为80．8％、75．8％、65．8％、45．0％、35．0％，联合测定后阳性率提高到95．8％。结论Fer、LN、CEA、β-HCG、AFP联合测定对于胸水和腹水性质的鉴别具有重要价值。
Objective To explore the use of laboratory testing index system to identify the quality of hydrothorax and hydroperitoneum. Methods The a-fetoprotein (AFP),carcinoembryonic antigen (CEA ), ferritin (Fer), β2-microglobulin (β2-MG ), human chorionic gonadotropin (PHCG ), ceruloplasmin (CP), hyaluronic acid (HA ) and laminin (LN)in the hydrothorax and hydroperitoneum of 251 patients were detected through radioimmunoassay. Results The Fer, LN, CEA, β-HCG and AFP showed significant differencesbetween the benign and malignant hydrothorax and hydroperitoneum (P<0.01), andthe positive rates of them were 80. 8%, 75. 8%, 65. 8%, 45. 0%, 35. 0% respectively.The positive rates could go up to 95. 8% after the combined detection. Conclusion Thecombined detection of Fer,LN,CEA,β-HCG and AFP has great value in identifying thequality of hydrothorax and hydroperitbneum.
出处
《临沂医学专科学校学报》
1998年第4期289-292,共4页
Journal of Linyi Medical College
关键词
胸水
腹水
肿瘤
放射免疫
Hydrothorax
Hydroperitoneum
Tumor
Radioimmunoassay
