摘要
目的观察降纤酶治疗急性脑梗死的临床疗效。方法经临床和头部CT确诊急性脑梗塞60例，32例以降纤酶10u加生理盐水150ml静滴，1h滴完，1次/d，共用3d，并辅以胞二磷胆碱、脑复康等治疗。3周后进行疗效评定。结果治疗组基本治愈率37.5％，显著进步率46.9％，总有效率96.9％，临床疗效显著高于对照组（P＜0.01），治疗后纤维蛋白原、全血粘度和血浆粘度显著降低。结论降纤酶是治疗急性脑梗死安全有效的药物。
Objecitive To observe the effect of defibrase on acute cerebral infarction(ACI). Methods 60 cases of ACI were confirmed by their clinical symptoms and CT diagnosis. 32 cases were treated wlth 10 units of defibrase and 15oml of physiologicalsaline for an hour a day within three days. Cytibine diphosphate choline, acetamide pyiiolidone were used simultaneously as an aid. Results The curative rate of the treatmentgroup was 37. 5%,and the effective rate was 46. 9%,with the total effective rate being96. 9% and the clinically therapeutic effect was significantly higher than those of thecontrol group(Uc=3. 39, P<0.01). The fibrinogen,the whole blood viscosity and theplasmatic viscoslty of the treatment group were greatly lowered. Conclusion Defibrase isa safe and effective drug in treating ACI.
出处
《临沂医学专科学校学报》
1998年第4期269-271,共3页
Journal of Linyi Medical College
关键词
降纤酶
脑梗塞
治疗
Cerebral infarction
Defibrase
